Results 31 to 40 of about 19,015,309 (380)
British Journal of Pharmacology, 1975 1 Prostaglandins F1α and F2α caused contraction of the longitudinal muscle of both guinea‐pig isolated ileum and colon, apparently by acting directly on the muscle and on cholinergic nerves. They had little effect on ileal circular muscle.
A. Bennett, K. Eley, H. L. Stockley
semanticscholar +1 more source
BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022 Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley +1 more source
Cancer Biology & Therapy, 2020 Epithelial-Mesenchymal Transition (EMT) and angiogenesis are crucial events for development of aggressive and often fatal Oral Squamous Cell Carcinomas (OSCCs).
Angela Santoro +12 more
doaj +1 more source
The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense
BioFactors, Volume 48, Issue 6, Page 1217-1225, November/December 2022., 2022 Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo +2 more
wiley +1 more source
An extension of a theorem of Zermelo [PDF]
Bull. symb. log 25 (2019) 208-212, 2018 We show that if (M,E,E') satisfies the first order Zermelo-Fraenkel axioms of set theory when the membership relation is E and also when the membership relation is E', and in both cases the formulas are allowed to contain both E and E', then (M,E) and (M,E') are isomorphic, and the isomorphism is definable in (M,E,E').
arxiv +1 more source
PLoS Biology, 2021 Intrauterine infection/inflammation (IUI) is a major contributor to preterm labor (PTL). However, IUI does not invariably cause PTL. We hypothesized that quantitative and qualitative differences in immune response exist in subjects with or without PTL ...
Monica Cappelletti +11 more
doaj +1 more source
Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation
Science, 2011 A new tissue-specific pathway for the synthesis of proinflammatory prostaglandins is described. Phospholipase A2(PLA2) enzymes are considered the primary source of arachidonic acid for cyclooxygenase (COX)–mediated biosynthesis of prostaglandins.
Daniel K. Nomura +10 more
semanticscholar +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022 Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan +4 more
wiley +1 more source
FACTORS REGULATING THE BIOSYNTHESIS OF VARIOUS PROSTAGLANDINS
Annals of the New York Academy of Sciences, 1971 the Karolinska Institute working in collaboration with Professor B. Samuelsson. At that time we were able to develop thin-layer techniques which allowed quantitative measurement of the many different products appearing during prostaglandin biosynthesis ...
W. Lands, Ronald Lee, W. Smith
semanticscholar +1 more source
Metabolism of prostaglandins E, A, and C in serum
Journal of Biological Chemistry, 1975 Three prostaglandin-metabolizing enzymes were detected in human serum. One enzyme was a dehydrase that converted prostaglandin E to prostaglandin A, the second was a prostaglandin A isomerase that converted prostaglandin A to prostaglandin C and the third was a prostaglandin C isomerase that converted prostaglandin C to prostaglandin B.
L Levine, H Polet
openaire +3 more sources