Results 121 to 130 of about 131,150 (281)

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long-Term Neuroprotection After Traumatic Brain Injury in Mice. [PDF]

Adv Sci (Weinh)
Pischiutta F, Tribuzio F, Magatti M, De Simone G, Moro F, Nattino G, Signorini F, Loose L, Caruso E, Bertani C, Mazzone E, Pascente R, Micotti E, Silini AR, Ortolano F, Trolese MC, Bolis M, Guarrera L, Violatto MB, Bigini P, Banfi C, Pastorelli R, Parolini O, Brunelli L, Zanier ER.   +24 more
europepmc   +1 more source

The antagonism of platelet-activating factor and hyperacute organ rejection [PDF]

, 1990
Banner, B, Chapman, F, Makowka, L, Mazzaferro, V, Pascualone, A, Podesta, L, Qian, S, Saunders, R, Sher, L, Sico, E, Starzl, TE, Sun, H, Zerbe, TR   +12 more
core  

Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators

Allergy, EarlyView.
Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo   +14 more
wiley   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Improved de novo production of prostaglandin F_2α from glucose with engineered Yarrowia lipolytica strains. [PDF]

Commun Biol
He GW, Ding LM, Fan X, Wang C, Lu XY, Tian Y, Ji XJ, Huang H, Liu HH.   +8 more
europepmc   +1 more source

Intracellular control of renin release - an overview [PDF]

, 1986
Kurtz, Armin
core   +1 more source

Toll‐like receptor 4 mediates lipopolysaccharide‐induced emesis

British Journal of Pharmacology, EarlyView.
Background and Purpose Lipopolysaccharide (LPS) induces inflammation and sepsis through Toll‐like receptor 4 (TLR4) activation. Common laboratory animals do not exhibit emesis, but administration of LPS in piglets, cats, and dogs induces emesis via peripheral mechanisms.
Luping Liu, Zengbing Lu, Julia Yuen Hang Liu, Man Piu Ngan, Kai‐Hei Tse, John Anthony Rudd   +5 more
wiley   +1 more source

Structural basis for prostaglandin and drug transport via SLCO2A1. [PDF]

Nat Commun
Joshi C, Deme JC, Nakamura Y, Hsu WT, Goult JD, Kato T, Parker JL, Biggin PC, Lea SM, Nakanishi T, Newstead S.   +10 more
europepmc   +1 more source

Cortisol and heart rate response of mares during the in‐hand breeding procedure with and without restraint

Equine Veterinary Journal, EarlyView.
Abstract Background In‐hand breeding involving restraint methods is likely the most common practice in the horse breeding industry worldwide. However, welfare issues that arise from such management have not been investigated in detail. Objectives (1) To investigate whether the mares show increased stress responses during in‐hand breeding using (a) a ...
Maria Fernanda Atayde, Beatriz Vidondo, Rupert Bruckmaier, Sabrina Briefer Freymond, Harald Sieme, Rebekka Rey‐Kaeser, Dominik Burger   +6 more
wiley   +1 more source