Results 131 to 140 of about 131,150 (281)

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer. [PDF]

Int J Mol Sci
Macia Guardado M, Lutz V, Hengstschläger M, Dolznig H.   +3 more
europepmc   +1 more source

Steroidogenic compensation and lipid deficiency with enhanced NAD+ salvage in small‐for‐gestational‐age placenta

The FEBS Journal, EarlyView.
Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo, Lorenza Driul, Vanessa Tolotto, Eros Di Giorgio, Luigi E. Xodo   +4 more
wiley   +1 more source

Labor Induction with Synthetic Oxytocin and Infantile Colic: A Case-Control Study. [PDF]

Medicina (Kaunas)
Suárez-Fraga C, Rodríguez-Nogueira Ó, Pinto-Carral A, Leirós-Rodríguez R, Álvarez-Álvarez MJ.   +4 more
europepmc   +1 more source

ALOX15 mediates thrombin‐induced myristoylation, trafficking, and interaction of protease‐activated receptors, leading to platelet activation and hemostasis

The FEBS Journal, EarlyView.
The role of PARs in platelet function is fairly known; however, the underlying mechanisms are not fully understood. We report that thrombin myristoylates PAR4 in mouse platelets and PAR1 and PAR4 in human platelets, facilitating their membrane transport and interaction, leading to PAR3/4 heterodimers in mice and PAR1/4 heterodimers in humans.
Suresh Govatati, Chandra Sekhar Yadavalli, Md Monirul Hoque, Swapna Thota, Gadiparthi N. Rao   +4 more
wiley   +1 more source

A bioprinted model of pregnant human uterine myometrium. [PDF]

Front Bioeng Biotechnol
Ulrich C, Siddiqui K, Baldwin LK, Hua W, Kuklok JK, Okaikoi JJ, Parker LL, Petereit J, Quilici DR, Silva GM, Sivakoses A, Wong-Fortunato JS, Woolsey RJ, West A, Jin Y, Burkin H.   +15 more
europepmc   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro. [PDF]

Environ Int
Land KL, Xu H, Akin JW, Hannon PR.
europepmc   +1 more source

Dual Beneficial Effects of Topical l‐Glutamine on Oral Mucositis in 5‐Fluorouracil‐Treated Mice

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Oral mucositis is a severe health and economic problem that occurs in about 40%–90% of patients undergoing cancer treatments. Systemic or topical application of l‐glutamine has been shown to improve mucosal healing and ameliorate oral mucositis (OM) symptoms according to clinical score systems.
Juliana Francisca Grossi Heleno, Igor de Campos Fontes, Leticia Cristine Cardoso dos Santos, Victor Prokop Gonçalves Campos, Iury Berckmann Freitas Gomes, Derek William Gilroy, Silvia Passos Andrade, Paula Peixoto Campos   +7 more
wiley   +1 more source

Black Gold in Medicine: Rediscovering the Pharmacological Potential. [PDF]

Molecules
Hashimova U, Gaisina A, Safikhanova K.
europepmc   +1 more source