ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani +3 more
wiley +1 more source
<i>Arthrospira platensis</i> Preserves Uterine Function by Modulating Electromechanical Coupling and Redox Pathways During Resistance Training in Female Rats. [PDF]
Barros BC +7 more
europepmc +1 more source
Insect‐Derived Bioactives for Glycemic Control and Gut Health: A Review
Insect‐derived bioactive compounds (e.g., peptides, polysaccharides) effectively regulate blood glucose through dual mechanisms: directly inhibiting carbohydrate‐digesting enzymes and glucose transporters, and indirectly modulating gut microbiota to enhance intestinal barrier integrity.
Chaoyi Lv +5 more
wiley +1 more source
Recent Advances in Isatin-Thiazole Hybrids: Synthesis, Structural Design, and Biological Application. [PDF]
Andrade IMG +4 more
europepmc +1 more source
Prostaglandin D2 Synthase Controls Schwann Cells Metabolism and Peripheral Myelin Homeostasis
Prostaglandin D2 Synthase (L‐PGDS) controls PPNS myelin lipids’ composition and Schwann cells energetic metabolism In the absence of L‐PGDS Schwann cells turn to acetate as the main energetic source. These metabolic changes result in ketone bodies production to preserve neuronal survival.
Amelia Trimarco +16 more
wiley +1 more source
Therapeutic Potential of Latin American Medicinal Plants in Oral Diseases: From Dental Pain to Periodontal Inflammation-A Systematic Review. [PDF]
Ramírez-Torres V +4 more
europepmc +1 more source
Tocolytic agents and the failure to improve neonatal outcomes
Abstract Premature delivery has long been a major problem in obstetrics. Increased perinatal morbidity and mortality as well as substantial health care costs, both short and long term, have driven the efforts to combat this complication. While multiple agents have been studied over the last 70 years leading to hundreds of publications and involving ...
Jack FitzSimmons, Emily Oliver
wiley +1 more source
Protective effect of Spirulina and <i>Lagenaria siceraria</i> on betamethasone adverse effects in rats. [PDF]
AbdelKhalek FE +5 more
europepmc +1 more source
Equine endometrium can develop progressive fibrotic and functional alterations, probably correlated with age and inflammatory insults that alter uterine microenvironment, creating hostile conditions for embryo implantation. Named chronic degenerative endometritis, this condition leads to reduced fertility in older mares. Extracellular vesicles secreted
Giulia Gaspari +10 more
wiley +1 more source
Evaluation of molecular mechanisms of (Z)-3-(pentadec-10'-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis. [PDF]
Cossu AM +16 more
europepmc +1 more source

