Results 201 to 210 of about 36,822 (231)

Glucosinolate-Derived Metabolites from <i>Barbarea vulgaris</i> (Brassicaceae): Evaluation of Antimicrobial, Antioxidant, and Anti-Inflammatory Potentials. [PDF]

Molecules
Mavrić-Scholze E, Gusinac A, Dekić M, Palić I, Avdović E, Simijonović D, Grujović M, Marković K, Dobričić V, Bošković J, Marković Z, Radulović N.   +11 more
europepmc   +1 more source

Physiological roles of fatty acids and endocannabinoids in the nematode Caenorhabditis elegans [PDF]

Reisner, Kaja
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Synthetic Modification of Prostaglandin F2α Indicates Different Structural Determinants for Binding to the Prostaglandin F Receptor Versus the Prostaglandin Transporter

Molecular Pharmacology, 2000
Several principles governing the binding of E series prostaglandins to EP receptors have emerged in recent years. The C-1 carboxyl group binds electrostatically to a conserved arginine residue in the seventh transmembrane segment of the receptor. Prostaglandin E analogs involving bioisosteric replacements of the carboxyl group, such as acylsulfonamide,
V L, Schuster, S, Itoh, S W, Andrews, R M, Burk, J, Chen, K M, Kedzie, D W, Gil, D F, Woodward   +7 more
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THE TERMINATION OF PREGNANCY BY INTRAVENOUS INFUSION OF A SYNTHETIC PROSTAGLANDIN F_2α ANALOGUE

BJOG: An International Journal of Obstetrics & Gynaecology, 1973
SummaryA synthetic analogue of prostaglandin F2α was successfully used to induce abortion in six patients, five of whom were in the second trimester of pregnancy. Five of the patients had a complete abortion and in one the abortion was incomplete. The mean induction‐abortion interval was 25 hours 15 minutes, ranging from 7 hours 45 minutes to 49 hours ...
D S, Sharp, R W, Burslem
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Therapeutic uses of prostaglandin F2α analogues in ocular disease and novel synthetic strategies

Prostaglandins & Other Lipid Mediators, 2013
The pharmacological management of glaucoma and ocular hypertension has significantly changed over the last 18 years with the introduction of PGF2α analogues, more specifically latanoprost (6), travoprost (8), bimatoprost (10) and tafluprost (12). Prostanoids are currently the first-line medicines among ocular antihypertensive drugs in terms of efficacy,
Iwona, Dams, Jaromir, Wasyluk, Marek, Prost, Andrzej, Kutner   +3 more
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Prostaglandin F_2α Binding to Bovine Ocular and Synthetic Melanins in Vitro

Pharmacology & Toxicology, 1989
Abstract: The binding of 3H‐prostaglandin F2α to bovine iris and synthetic melanin was studied in vitro using a ligand binding assay. Prostaglandin F2α was reversibly bound to both types of melanin. The binding was saturable and the Scatchard analysis revealed the existence of at least two binding sites with the corresponding KD values of 3.71 nM and ...
P, Aula, T, Kaila, R, Huupponen, L, Salminen, E, Iisalo   +4 more
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ChemInform Abstract: SYNTHETIC STUDIES ON PROSTANOIDS PART 5, TOTAL SYNTHESIS OF PROSTAGLANDIN E1 AND F(1BETA)

Chemischer Informationsdienst, 1975
AbstractDie nach früheren Untersuchungen aus (I) und ‐(II) gut zugängliche Cyclohexan‐Zwischenstufe (III) wird in der angegebenen Weise zur Synthese von Prostaglandin E1 (IX) und Prostaglandin F1 (VIII) eingesetzt.
K. KOJIMA, K. SAKAI
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Mass spectrometric determination of picomole amounts of prostaglandins E2 and F2α using synthetic deuterium labeled carriers

Biochemical and Biophysical Research Communications, 1971
Abstract [3,3,4,4-D 4 ]-prostaglandin E 2 and [3,3,4,4-D 4 ]-prostaglandin F 2α were prepared and used as carriers in quantitative gas chromatography-mass spectrometry. Ions of the protium form and the tetradeuterio form produced by electron impact on the effluent were monitored.
U, Axen, K, Gréen, D, Hörlin, B, Samuelsson   +3 more
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Effect of Prostaglandin F₂α and its Synthetic Analogue on Retention of Spermatozoa in the Reproductive Tract of Estrous Rabbits

Reproduction in Domestic Animals, 1985
Contents 15 estrous does were used to determine whether PGF 2α(dinoprost) or synthetic PGF2α(cloprostenol) administered to does shortly (10 min.) after artificial deposition of 100 × 106sperm cells in the cranial vagina would increase the retention of sperm in the reproductive tract. The animals were divided into 3 equal poups.
A.A. El‐Menoufy, A.A. Radwan, M.M. El‐Habbak   +2 more
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Coupling between cyclooxygenases and prostaglandin F(2alpha) synthase. Detection of an inducible, glutathione-activated, membrane-bound prostaglandin F(2alpha)-synthetic activity.

Biochimica et biophysica acta, 2003
Distinct functional coupling between cyclooxygenases (COXs) and specific terminal prostanoid synthases leads to phase-specific production of particular prostaglandins (PGs). In this study, we examined the coupling between COX isozymes and PGF synthase (PGFS).
Karin, Nakashima, Noriko, Ueno, Daisuke, Kamei, Toshihiro, Tanioka, Yoshihito, Nakatani, Makoto, Murakami, Ichiro, Kudo   +6 more
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