Results 21 to 30 of about 9,574,868 (208)
Prostanoid Signaling in Cancers: Expression and Regulation Patterns of Enzymes and Receptors
Biology, 2022 Cancer-associated disturbance of prostanoid signaling provides an aberrant accumulation of prostanoids. This signaling consists of 19 target genes, encoding metabolic enzymes and G-protein-coupled receptors, and prostanoids (prostacyclin, thromboxane ...
Pavel V. Ershov +4 more
doaj +1 more source
Journal of Biological Chemistry, 2001 Electrophilic eicosanoids of the J series, with their distinctive cross-conjugated α,β-unsaturated ketone, inactivate genetically wild type tumor suppressor p53 in a manner analogous to prostaglandins of the A series.
J. Mullally +3 more
semanticscholar +1 more source
Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes. [PDF]
PLoS Neglected Tropical Diseases, 2013 Trypanosoma cruzi, the causative agent of Chagas' disease, induces multiple responses in the heart, a critical organ of infection and pathology in the host.
Ricardo S Corral +4 more
doaj +1 more source
Enzymic separatory determination of prostaglandin F and F.
Chemical and Pharmaceutical Bulletin, 1975 A simple and sensitive method is described for separatory determination of prostaglandin E and prostaglandin F. This method is based on three principles : (1) Prostaglandin E and prostaglandin F are oxidized by prostaglandin dehydrogenase, resulting reduced nicotinamide-adenine dinucleotide (NADH).
T, Itami +3 more
openaire +3 more sources
Colocalization of prostaglandin F2α receptor FP and prostaglandin F synthase-I in the spinal cord [PDF]
Journal of Lipid Research, 2009 Prostaglandin F(2alpha) is synthesized by prostaglandin F synthase, which exists in two types, prostaglandin F synthase I (PGFS I) and prostaglandin F synthase II (PGFS II). Prostaglandin F(2alpha) binds to its specific receptor, FP. Our previous immunohistochemical study showed the distinct localization of prostaglandin F synthases in rat spinal cord.
T. Suzuki-Yamamoto +3 more
openaire +3 more sources
Molecules, 2018 Cyclooxygenase 2 (COX-2) is an inducible enzyme responsible for the conversion of arachidonic acid into the prostaglandins, PGG2 and PGH2. Expression of this enzyme increases in inflammation.
Michelle Y. Cortes-Salva +8 more
doaj +1 more source
Aldo keto reductase 1B7 and prostaglandin F2alpha are regulators of adrenal endocrine functions. [PDF]
PLoS ONE, 2009 Prostaglandin F(2alpha) (PGF(2alpha)), represses ovarian steroidogenesis and initiates parturition in mammals but its impact on adrenal gland is unknown.
Sarah Lambert-Langlais +13 more
doaj +1 more source
Uterine luminal prostaglandin F in cycling mares
Prostaglandins, 1978 Prostaglandin F was measured by radioimmunoassay in uterine flushings of cycling mares on days 4, 8, 12, 14, 16, 18 and 20 post-ovulation. Prostaglandin F was significantly (P less than .05) affected by day of the estrous cycle and reached maximal levels on day 14.
Departments of Animal Science and Dairy Science University of Florida, Gainesville, Florida 32611, USA ( host institution ) +5 more
openaire +3 more sources
Role of aldo-keto reductase enzymes in mediating the timing of parturition
Frontiers in Pharmacology, 2012 A better understanding of the mechanisms underlying the initiation of parturition would provide an important step towards the development of more effective therapies for the prevention of pre-term labor and the associated neonatal morbidity and mortality.
Michael C. Byrns
doaj +1 more source
Ixodes ricinus tick lipocalins: identification, cloning, phylogenetic analysis and biochemical characterization. [PDF]
PLoS ONE, 2008 BACKGROUND: During their blood meal, ticks secrete a wide variety of proteins that interfere with their host's defense mechanisms. Among these proteins, lipocalins play a major role in the modulation of the inflammatory response.
Jérôme Beaufays +9 more
doaj +1 more source