Results 1 to 10 of about 648,642 (402)
Review on the simultaneous determination of total prostate-specific antigen and free prostate-specific antigen [PDF]
The Prostate, 2004 The total prostate-specific antigen (t-PSA) in serum measured by PSA assays represents the sum of free (f-PSA) and PSA complexed with alpha 1-antichymotrypsin. The f-PSA/t-PSA (F/T) ratio in prostate cancer (PCA) patients is lower than in patients suffering from benign prostatic hyperplasia (BPH).
C.M. G. Thomas +5 more
core +11 more sources
Prostate specific antigen [PDF]
Australian family physician, 2011 The use of PSA as a screening test for prostate cancer remains controversial because no double blind, randomised controlled trial has shown that early detection reduces mortality.1,2 Despite this controversy, PSA provides valuable information for the ...
Brett, Tom
core +5 more sources
Prostate Specific Antigen: A review [PDF]
Acta Oncologica, 1991 Despite its identification in the 1970s, prostate specific antigen (PSA) has only recently gained widespread utility. In this review, we will describe significant aspects of the biochemistry of PSA, immunohistochemical applications, the effect of prostatic manipulation on the serum level of this analyte, and other considerations in the determination of
M K Brawer
openalex +4 more sources
Prostate-specific antigen and prostate-specific antigen density cutoff points among Indonesian population suspected for prostate cancer [PDF]
Prostate International, 2013 Racial differences exist in the incidence of prostate cancer (PCa). Although many studies have looked at the performance of prostate-specific antigen (PSA) and PSA density (PSAD) in the detection of PCa, only a few have looked at it in relation to ...
Ahmad Anies Shahab +5 more
doaj +6 more sources
The Additional Value of Free Prostate Specific Antigen to the Battery of Age-Dependent Prostate-Specific Antigen, Prostate-Specific Antigen Density and Velocity [PDF]
Clinical Chemistry and Laboratory Medicine, 1997 This study describes the value of using the fraction of free prostate-specific antigen as a further marker in the early detection of prostate cancer. This newly introduced marker is compared to the usual battery of age-dependent total prostate-specific antigen, prostate-specific antigen density (microg/l x g tissue) and prostate-specific antigen ...
Mira Barak +6 more
openalex +4 more sources
Pretreatment tumor volume estimation based on total serum psa in patients with localized prostate cancer [PDF]
Clinics, 2008 OBJECTIVES: To establish a formula that estimates tumor volume in localized prostate cancer based on serum prostate specific antigen levels. One of the main prognostic variables in localized prostate cancer is tumor volume, which can be precisely defined
Raphael Barroso Kato +5 more
doaj +5 more sources
Asian Journal of Andrology, 2017 We investigated the performance characteristics of prostate-specific antigen (PSA) and PSA density (PSAD) in Chinese men. All Chinese men who underwent transrectal ultrasound-guided prostate biopsy (TRUS-PB) from year 2000 to 2013 were included.
Jeremy YC Teoh +8 more
doaj +4 more sources
Asian Journal of Andrology, 2022 The goal of this study was to investigate the clinical application of free/total prostate-specific antigen (F/T PSA) ratio, considering the new broad serum total PSA (T-PSA) “gray zone” of 2.0–25.0 ng ml−1 in differential diagnosis of prostate cancer ...
Xue-Dan Gao +7 more
doaj +1 more source
Mathematical Modeling Insights into Improving CAR T cell Therapy for Solid Tumors: Antigen Heterogeneity and Bystander Effects [PDF]
npj Systems Biology and Applications, 10(1), 105 (2024), 2023 As an adoptive cellular therapy, Chimeric Antigen Receptor T-cell (CAR T-cell) therapy has shown remarkable success in hematological malignancies, but only limited efficacy against solid tumors. Compared with blood cancers, solid tumors present a unique set of challenges that ultimately neutralize the function of CAR T-cells.
arxiv +1 more source
Body mass index in relation to prostate-specific antigen-related parameters
BMC Urology, 2021 Background Only a few previous studies conducted to assess the association between body mass index (BMI) and prostate-specific antigen (PSA) related parameters have taken prostate volume (PV) and blood volume (BV) into consideration.
Dandan Lin +3 more
doaj +1 more source