Results 131 to 140 of about 95,272 (257)

Clinical Relevance of BACH1 Expression in Non–Small Cell Lung Cancer

International Journal of Cancer, EarlyView.
ABSTRACT BTB and CNC homolog 1 (BACH1) is a redox‐sensitive transcription factor implicated in tumor progression, metabolic reprogramming, and therapy resistance in several cancers. However, its prognostic significance and role in therapy resistance in non–small cell lung cancer (NSCLC) remain unclear.
Jing Liu, Marc A. Schneider, Julia Held, Sabine Wrenger, Wenzhang Si, Michael Allgaeuer, Florian Eichhorn, Sabina Janciauskiene   +7 more
wiley   +1 more source

Integrating Prostate-Specific Antigen Density and Prostate Imaging Reporting and Data System Scores to Optimize Detection of Clinically Significant Prostate Cancer: A Multivariable Risk Model Approach. [PDF]

J Clin Lab Anal
Kayali Y.
europepmc   +1 more source

Prostate-specific Antigen Density Cutoff of 0.15 ng/ml/cc to Propose Prostate Biopsies to Patients with Negative Magnetic Resonance Imaging: Efficient Threshold or Legacy of the Past? [PDF]

Eur Urol Focus, 2023
Pellegrino F, Tin AL, Martini A, Vertosick EA, Porwal SP, Stabile A, Gandaglia G, Eastham JA, Briganti A, Montorsi F, Vickers AJ.   +10 more
europepmc   +1 more source

Tumour Antigen‐Specific Antibody Signatures as Diagnostic Biomarkers for Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT Early detection of melanoma remains challenging, and minimally invasive diagnostic tools are needed to complement imaging and histopathology. Circulating tumour antigen‐specific antibodies (Abs) are promising biomarkers, but their diagnostic value across melanoma stages is not fully established.
Cristina Vico‐Alonso, Tawany De Carvalho Gil, Maithili Sashindranath, Victoria Mar, Jessica Da Gama Duarte   +4 more
wiley   +1 more source

Diagnostic Value of Transabdominal Ultrasound-based Versus Magnetic Resonance Imaging-based Prostate-specific Antigen Density for Clinically Significant Prostate Cancer. [PDF]

Eur Urol Open Sci
Xu Z, Song H, Huang H, Fu M, Tang Y, Zhang P, Zhang G, Li J.   +7 more
europepmc   +1 more source

The role of prostate-specific antigen density and negative multiparametric magnetic resonance imaging in excluding prostate cancer for biopsy-naïve men: clinical outcomes from a high-volume center in China. [PDF]

Asian J Androl, 2022
Zhang CC, Tu X, Lin TH, Cai DM, Yang L, Nie L, Qiu S, Liu ZH, Jin K, Li JK, Xiong XY, Yang L, Wei Q.   +12 more
europepmc   +1 more source

MLH1 p.His112Arg Variant Is Associated With Increased Cancer Susceptibility

International Journal of Cancer, EarlyView.
ABSTRACT Lynch syndrome, a prevalent hereditary cancer predisposition, is frequently caused by pathogenic variants in the MutL homolog 1 (MLH1) mismatch repair gene. However, a significant proportion of MLH1 missense variants remain classified as variants of uncertain significance (VUS), creating clinical ambiguity.
Amal Elfatih, Issam Tout, Najwa Ahmad Doha, Tala Abu Arja, Idris Mohammed, Doua Abdelrhaman, Waseem Hasan, Chadi Saad, Hamdi Mbarek, Borbala Mifsud, Sahar Isa Da'as   +10 more
wiley   +1 more source

Omitting biopsy in Prostate Imaging Reporting and Data System 3? The role of Stockholm3 and prostate-specific antigen density findings from a prospective Swiss non-referral cohort. [PDF]

Prostate Int
Arnold N, Mudlagk J, Minder O, Cornelius J, Di Bona C, Roth B, Mordasini L, Giudici N.   +7 more
europepmc   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

iMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang, Jinfei Liu, Qiangsheng Wang, Lei Fan, Ziang Li, Xuexin Yu, Yonghao Chen, Xiaofan Lu, Guiyi Liao, Jialin Meng, Yu Guan   +10 more
wiley   +1 more source

Automating prostate volume acquisition using abdominal ultrasound scans for prostate-specific antigen density calculations. [PDF]

Sci Rep
Bennett RD, Barrett T, Sushentsev N, Sanmugalingam N, Lee KL, Gnanapragasam VJ, Tse ZTH.   +6 more
europepmc   +1 more source