Results 151 to 160 of about 95,272 (257)

Association of Prostate Imaging Reporting and Data System (PI-RADS) Score and Prostate-Specific Antigen Density (PSAD) With Prostate Biopsy Histology Outcomes: A Retrospective Study. [PDF]

Cureus
Balasubaramaniam V, Agarwal A, Kailasa A, Ismail NAB, Grogan D, Shoker A, Rhodes KV, Donev K, Kannan S.   +8 more
europepmc   +1 more source

Liquid biopsy across cancers: Integrating circulating biomarkers, tumor biology, artificial intelligence, and clinical translation

Interdisciplinary Medicine, EarlyView.
Liquid biopsy uses non‐invasive sampling of blood or body fluids to isolate circulating analytes, including circulating tumor DNA, circulating tumor cells, extracellular vesicles, and RNA. These are analyzed using next‐generation sequencing, qPCR, and proteomics to inform cancer detection, monitoring, and characterization. Figure created with BioRender.
Jaswinder Singh, Manjeet Kumar, Kajal Kamra   +2 more
wiley   +1 more source

Incidental prostate cancer: is prostate-specific antigen density a valid predictor? A case-control study. [PDF]

Ther Adv Urol
Farzat M, Wagenlehner FM.
europepmc   +1 more source

An independent practice validation of the Prostate Imaging Reporting and Data System version 2 scoring system and the introduction of PDP (prostate-specific antigen density × PI-RADSv2) score to assist with further risk assessment. [PDF]

Curr Urol, 2022
Patel PU, Bock D, Hettinger CA.
europepmc   +1 more source

Risk Stratification of Prostate Imaging Reporting and Data System (PI‐RADS 3) Lesions in the Peripheral and Transition Zones Using Clinical and Quantitative MRI Markers

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Prostate Imaging Reporting and Data System (PI‐RADS) 3 lesions often undergo biopsy despite a low positive predictive value (< 25%) for clinically significant prostate cancer (csPCa), defined as International Society of Urological Pathology (ISUP) Grade Group ≥ 2.
Tejinder Kaur, Reve Chahine, Nicole Seiberlich, Hero Hussain, Shane Wells, Vikas Gulani, Yun Jiang   +6 more
wiley   +1 more source

A two‐stage model for precise identification and Gleason grading of clinically significant prostate cancer: a hybrid approach

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 93-105, March 2025.
This study developed a two‐stage model using radiomics‐based multiparametric MRI and clinical indicators to help identify and grade clinically significant prostate cancer. The model showed promising levels of diagnostic accuracy and predictive performance.
Yuyan Zou, Xuechun Wang, Fen Ma, Xulun Liu, Chunyue Jiao, Zhen Kang, Jingjing Cui, Yang Zhang, Yan Xie, Lei Chen, Ronghua Tian   +10 more
wiley   +1 more source

Effect of prostate volume on the predictive value of prostate-specific antigen density for prostate cancer. [PDF]

Transl Androl Urol
Liu Z, Yu Y, Hu R, Jian T, Yu K, Lu J.
europepmc   +1 more source

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

Prostate-specific antigen density does not predict metastatic disease on PSMA-PET in high-risk prostate cancer patients with negative conventional imaging. [PDF]

Can Urol Assoc J
Kumar R, Lajkosz K, Metser U, Misurka J, Hiemstra J, Kreidstein J, Calicchia L, Silberman A, Finelli A, Fleshner NE, Hamilton RJ, Kulkarni GS, Zlotta A, Berlin A, Perlis N.   +14 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification of TXNDC5 mRNA Promotes Cervical Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT WT1‐associated protein (WTAP), a core component of the methyltransferase complex, is involved in various tumor pathological processes, but its specific mechanism in cervical cancer (CC) remains unclear. This study, based on single‐cell transcriptomic data (including 3 CC and 2 normal tissues), constructed a CC microenvironment cell atlas ...
Ling Chen, Nuo‐Xin Hu, Zhao‐Ying Chen, Ke‐An Zhu, Wei Huang   +4 more
wiley   +1 more source