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Diagnostic Performance of Prostate-specific Antigen Density for Detecting Clinically Significant Prostate Cancer in the Era of Magnetic Resonance Imaging: A Systematic Review and Meta-analysis. [PDF]

Eur Urol Oncol
Wang S, Kozarek J, Russell R, Drescher M, Khan A, Kundra V, Barry KH, Naslund M, Siddiqui MM.   +8 more
europepmc   +1 more source

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TRANSITION ZONE PROSTATE SPECIFIC ANTIGEN DENSITY

The Journal of Urology, 1998
Among the new approaches to enhance the performance of prostate specific antigen (PSA) testing in a biopsy population is the use of the free-to-total PSA as well as the transition zone density, which is calculated by dividing the PSA by the transition zone volume.
D W, Lin, M H, Gold, S, Ransom, W J, Ellis, M K, Brawer   +4 more
openaire   +3 more sources

PROSTATE-SPECIFIC ANTIGEN DENSITY

Urologic Clinics of North America, 1997
Nearly 20 years have passed since PSA was definitively identified. Throughout this period, its clinical application as a tumor marker has expanded significantly. Today, besides monitoring prostate cancer therapy, PSA is being used extensively in mass screening programs for early detection of adenocarcinoma of the prostate and has become the most ...
M C, Beduschi, J E, Oesterling
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Comparison of Prostate Specific Antigen with Prostate Specific Antigen Density for 3 Clinical Applications

Journal of Urology, 1994
We compared prostate specific antigen (PSA) to PSA density for 3 clinical uses: detection of nonpalpable prostate cancer, staging of clinically localized prostate cancer and prediction of PSA detectability following radical prostatectomy. Of 153 men with normal digital rectal examinations undergoing prostate biopsy 25% had prostate cancer.
K, Shinohara, J S, Wolf, P, Narayan, P R, Carroll   +3 more
openaire   +2 more sources

Prostate specific antigen and prostate specific antigen density. Roles in patient evaluation and management

Cancer, 1994
Prostate specific antigen (PSA) is the most accurate serum marker for prostate cancer. However, sensitivity and specificity are suboptimal, especially at the intermediate levels between 4.1 and 10.0 ng/ml (monoclonal). For intermediate PSA levels, PSA density (PSAD) provides unique information regarding the need for biopsy and the likelihood of ...
M C, Benson, C A, Olsson
openaire   +2 more sources

Serum Prostate Specific Antigen and Prostate Specific Antigen Density in Patients Receiving Radical Prostatectomy

International Journal of Urology, 1996
Objective: To study the significance of prostate specific antigen (PSA) and prostate specific antigen density (PSAD) for predicting the risk of occult metastatic disease and extra‐prostatic invasion of prostate cancer in patients receiving radical prostatectomy.Patients and methods: The cases of 41 consecutive patients who underwent radical ...
M, Masai, H, Ito, T, Kotake, K, Nagao
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Effect of finasteride on prostate-specific antigen density

Urology, 1994
Prostate-specific antigen density (PSAD) has been proposed as a diagnostic marker for prostate cancer. Because treatment with finasteride may affect PSAD differently in men with BPH compared with men with BPH plus prostate cancer, we evaluated the diagnostic utility of PSAD in men treated with finasteride for twelve months.Data for this analysis were ...
G J, Gormley, J, Ng, T, Cook, E, Stoner, H, Guess, P, Walsh   +5 more
openaire   +2 more sources

Role of prostate-specific antigen density after applying age-specific prostate-specific antigen reference ranges

Urology, 1995
To determine the potential role of prostate-specific antigen (PSA) density (PSAD) in the early detection of prostate carcinoma if we apply age-specific PSA reference ranges (2.5 ng/mL or less for ages 40 to 49 years, 3.5 or less for ages 50 to 59, 4.5 or less for ages 60 to 69, and 6.5 or less for ages 70 to 79.We retrospectively reviewed 3234 cases ...
A W, Meshref, M, Bazinet, C, Trudel, S, Aronson, F, Peloquin, M, Nachabe, J, Dessureault, A G, Aprikian, L R, Begin, M M, Elhilali   +9 more
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Correlation of prostate-specific antigen and prostate-specific antigen density with outcome of prostate biopsy

Urology, 1994
We attempt to correlate prebiopsy serum prostate-specific antigen (PSA) concentration and prostate-specific antigen density (PSAD) with histologic results of prostate biopsy.Sixty-two consecutive patients underwent prostate biopsy because of elevated PSA greater than 4 ng/mL and/or abnormal findings on digital rectal examination (DRE).
R, Bare, L, Hart, D L, McCullough
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Value of Prostate Specific Antigen Density and Percent Free Prostate Specific Antigen for Prostate Cancer Prognosis

Journal of Urology, 2012
Limited data exist on the relationship of percent free prostate specific antigen and prostate specific antigen density with prostate cancer prognosis. Therefore, we compared percent free prostate specific antigen and prostate specific antigen density with prostate specific antigen, Gleason sum and stage to predict prostate cancer prognosis in a large ...
Jonas, Busch, Kristin, Hamborg, Hellmuth-Alexander, Meyer, John, Buckendahl, Ahmed, Magheli, Michael, Lein, Klaus, Jung, Kurt, Miller, Carsten, Stephan   +8 more
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