Results 51 to 60 of about 95,272 (257)

Performance of PSA and of PSA density in the diagnosis of prostate carcinoma

Acta Cirúrgica Brasileira, 2002
OBJECTIVE: The aim of the study was to investigate the influence of the prostate volume and PSA density on the performance of total PSA to diagnosis of prostate carcinoma. METHODS: We analyzed 217 patients (PSA 0-10ng/ml) submitted to transrectal sextant
Antonio Carlos Pereira Martins, Tiago J. Borelli- Bovo, Rodolfo Borges dos Reis, Edson Luiz Paschoalin, Adauto José Cologna, Haylton Jorge Suaid   +5 more
doaj   +1 more source

Association between obesity, prostate-specific antigen level and prostate-specific antigen density in men with a negative prostate biopsy

Journal of International Medical Research, 2014
Objective To determine the association between body mass index (BMI), serum prostate-specific antigen (PSA) level and PSA density (PSAD) in patients with an elevated serum PSA level but a negative prostate biopsy. Methods
Jae Heon, Kim, Sang Wook, Lee, Jae Ho, Kim, Hee Jo, Yang, Seung Whan, Doo, Jong Hyun, Yoon, Doo Sang, Kim, Won Jae, Yang, Kwang Woo, Lee, Jun Mo, Kim, Changho, Lee, Soon-Sun, Kwon   +11 more
openaire   +2 more sources

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Evaluation of prostatic cancer prevalence in patients with prostatic-specific antigen between 4 and 10 and normal digital rectal examination

Advanced Biomedical Research, 2016
Background: Prostate cancer is one of the most common male cancers. The prevalence of prostate cancer is different due to genetic and environmental factors.
Farhad Tadayon, Hamid Reza Arezegar, Mohammad Hatef Khorrami, Rasoul Hashemi Juzdani, Amir Abbas Shahdoost, Mehdi Mellat   +5 more
doaj   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

EVALUATION OF THE EFFECTIVENESS OF MULTIFOCAL PUNCTURE BIOPSY IN THE DIAGNOSIS OF PROSTATE CANCER

Клінічна та профілактична медицина
Introduction. The value of multifocal puncture biopsy of the prostate is undoubtedly extremely important today for the timely diagnosis of prostate cancer.
Mykola D. Sosnin, Volodymyr O. Shaprynskyi, Viktor I. Gorovyi, Oleh M. Kapshuk, Volodymyr V. Danylko, Mykhailo A. Verba   +5 more
doaj   +1 more source

Rational Control of Antibody Orientation for Enhancing Sensitivity and Specificity in Lateral Flow Immunoassays With Clinical Validation

Advanced Healthcare Materials, EarlyView.
Systematic investigation of antibody orientation strategies in lateral flow immunoassays reveals that a para‐substituted (aminomethyl)phenylboronic acid mediated probe (P‐6) combined with a biotin‐streptavidin test‐line modification achieves a synergistic 14‐ to 19‐fold sensitivity gain over conventional conjugation. Furthermore, multiplexed detection,
Pin‐Hao Wang, Shunmuga Nathan Shunmuga Nainar, Bing‐Han Zhuang, Shun‐Mao Yang, Hong‐Cheu Lin, Yang‐Hsiang Chan   +5 more
wiley   +1 more source

Outcomes and complications after transrectal ultrasound-guided prostate biopsy: A single-center study involving 425 consecutive patients

Urological Science, 2018
Objective: The use of 10–12-core systemic transrectal ultrasound (TRUS)-guided prostate biopsy protocols with extended-sampling has been an optimizing strategy for diagnosis of prostate cancer.
Jhen-Hao Jhan, Shu-Pin Huang, Wei-Ming Li, Ching-Chia Li, Tsung-Yi Huang, Hung-Lung Ke, Chun-Nung Huang, Yii-Her Chou, Shen-Chen Wen   +8 more
doaj   +1 more source

Recent Advances in Light‐Addressable Electrochemistry for Spatially Resolved Applications

Advanced Materials Technologies, EarlyView.
This comprehensive review highlights light‐addressable electrochemistry as a powerful tool that uses light to control localized chemical reactions on unstructured semiconductor surfaces. The work evaluates advanced strategies to optimize electrode materials for enhanced spatial resolution and stability. Furthermore, it showcases diverse applications in
Nhi Trang Vo, Sina Jamali, Nam‐Trung Nguyen   +2 more
wiley   +1 more source

COMPARISON OF VALUE OF FREE-TO TOTAL PROSTATE SPECIFIC ANTIGEN, PROSTATE SPECIFIC ANTIGEN DENSITY AND PROSTATE SPECIFIC ANTIGEN DENSITY OF TRANSITION ZONE FOR DIAGNOSIS OF PROSTATE CANCER IN PATIENTS WITH A PSA LEVEL OF 4.1-10ng/ml

The Japanese Journal of Urology, 2005
We evaluated the utility of free-to total PSA (F/T PSA) ratio, PSA density (PSAD) and PSA density of the transition zone (PSATZ) in diagnosis of prostate cancer with intermediate PSA level (4.1-10 ng/ml).Between January 2000 and December 2003, systematic prostate biopsies were performed on 178 patients with intermediate PSA level.
Fujinami, Kiyoshi, Miura, Takeshi, Takizawa, Akitoshi, Osada, Yutaka, Kawakami, Satoshi   +4 more
openaire   +3 more sources