Results 31 to 40 of about 94,624 (285)

Diagnostic Performance of Prostate-specific Antigen Density for Detecting Clinically Significant Prostate Cancer in the Era of Magnetic Resonance Imaging: A Systematic Review and Meta-analysis [PDF]

European Urology Oncology
Shu Wang, Vikas Kundra, Kathryn Hughes Barry   +2 more
exaly   +2 more sources

AGE, TOTAL PSA, PSA DENSITY AND GLEASON SCORE, TAUS AS PREDICTIVE FACTORS IN PATIENTS WITH PROSTATE CANCER

Jurnal Urologi Indonesia, 2016
Objective: To find the factors related as predictive factors for Gleason score in prostate cancer patients. Material & methods: This study obtained a total sample of 144 patients with prostate cancer in Sardjito General Hospital Yogyakarta in 2009-2013 ...
Daruqutni Albar, Sungsang Rochadi
doaj   +1 more source

The Impact of prostate – Specific Antigen Density In Predicting Prostate Cancer

Diyala Journal of Medicine, 2019
The objective of this study is to evaluate the impact of prostate-specific antigen density ( PSDA ) when serum levels of prostate-specific antigen ( PSA ) are less than 10 ng\ml in predicting prostate cancer. We retrospectively analyzed 134 patients who
Abdul-Kareem Sh. Al-Khafaji, Baha'a-Eladeen A. Al-Mujammaey   +1 more
doaj   +2 more sources

Value of MRI to Improve Deep Learning Model That Identifies High-Grade Prostate Cancer. Comment on Gentile et al. Optimized Identification of High-Grade Prostate Cancer by Combining Different PSA Molecular Forms and PSA Density in a Deep Learning Model. Diagnostics 2021, 11, 335

Diagnostics, 2021
Prostate-specific antigen (PSA) has been criticized for its low specificity for prostate cancer, which has led to the increased adoption of additional biomarkers, PSA density (PSAD), and multiparametric magnetic resonance imaging (mpMRI) to increase the ...
Joshua S. Jue, David Mikhail, Javier González, Mahmoud Alameddine   +3 more
doaj   +1 more source

Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy

Nature Communications, 2023
Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface antigen for therapeutic targeting in prostate cancer. Here, we report broad expression of STEAP1 relative to prostate-specific membrane antigen (PSMA) in lethal metastatic ...
Vipul Bhatia, Nikhil V. Kamat, Tiffany E. Pariva, Li-Ting Wu, Annabelle Tsao, Koichi Sasaki, Huiyun Sun, Gerardo Javier, Sam Nutt, Ilsa Coleman, Lauren Hitchcock, Ailin Zhang, Dmytro Rudoy, Roman Gulati, Radhika A. Patel, Martine P. Roudier, Lawrence D. True, Shivani Srivastava, Colm M. Morrissey, Michael C. Haffner, Peter S. Nelson, Saul J. Priceman, Jun Ishihara, John K. Lee   +23 more
doaj   +1 more source

Peripheral zone PSA density: a predominant variable to improve prostate cancer detection efficiency in men with PSA higher than 4 ng ml-1

Asian Journal of Andrology, 2021
To improve the diagnostic efficiency of prostate cancer (PCa) and reduce unnecessary biopsies, we defined and analyzed the diagnostic efficiency of peripheral zone prostate-specific antigen (PSA) density (PZ-PSAD).
Cheng Wang, Yue-Yang Wang, Shi-Yuan Wang, Ji-Xiang Ding, Mao Ding, Yuan Ruan, Xiao-Hai Wang, Yi-Feng Jing, Bang-Min Han, Shu-Jie Xia, Chen-Yi Jiang, Fu-Jun Zhao   +11 more
doaj   +1 more source

Evaluation of Cutoff Point Prostate Specific Antigen (PSA) and Prostate Specific Antigen Density (PSAD) in Patients with Suspected Prostate Cancer. [PDF]

Med Arch
Background: Prostate cancer is the second leading cause of cancer death in men worldwide. There is no national standard for PSA cut-off levels even through the transrectal prostate biopsy procedure causes many serious complications such as bleeding, infection, and sepsis.
Daryanto B, Trianto R, Seputra KP, Purnomo AF.   +3 more
europepmc   +3 more sources

An investigation into minichromosomal maintenance proteins (MCMs) for the diagnosis of prostate cancer, as a possible alternative to prostate specific antigen (PSA) [PDF]

, 2005
The current strategy for the diagnosis of prostate cancer includes serum prostate specific antigen (PSA) measurement. There is however debate into its specificity and sensitivity, so new diagnostic markers are under investigation.
Watkins, Jane Louise
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Prostate-specific antigen density predicts favorable pathology and biochemical recurrence in patients with intermediate-risk prostate cancer

Asian Journal of Andrology, 2016
This study was designed to identify clinical predictors of favorable pathology and biochemical recurrence (BCR) in patients with intermediate-risk prostate cancer (IRPCa).
Ho Won Kang, Hae Do Jung, Joo Yong Lee, Jong Kyou Kwon, Seong Uk Jeh, Kang Su Cho, Won Sik Ham, Young Deuk Choi   +7 more
doaj   +1 more source