Results 131 to 140 of about 105,659 (312)

To investigate using morphometric and immunohistochemical criteria the relationship between prostatic intra-epithelial neoplasia and prostate cancer.

, 2006
Prostatic Intraepithelial Neoplasia (PIN) is a putatitive precursor of prostate carcinoma (CaP). PIN is defined as an abnormal proliferation where the cellular changes exhibit the cytological changes of cancer, but retain a basal cell layer.
Sandhu, Sarbjinder Singh, Sandhu, S.S.
core  

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

MUC1 as a Survival Effector of Radiotherapy‐Induced Epithelial Hybrid States in Basal‐Like Breast Cancer

International Journal of Cancer, EarlyView.
Basal‐like breast cancer (BLBC) is aggressive and often exhibits inherent or acquired resistance to radiotherapy (RT), a primary treatment option. RT resistance is underpinned by molecular alterations, many of which are poorly understood. Here, RT‐induced transcriptomic changes were analyzed using bulk and spatial sequencing in a BLBC mouse model and ...
Garyfallia Pantelaiou‐Prokaki, Husam Bamahmoud, Nadine S. Georges, Shaishavi Jansari, Annika Jung, Daniela Grimm, Evangelos Prokakis, Fabian Alexander Gayer, Maryam Deldar, Christian Dullin, Julia Gallwas, Florian Wegwitz, Frauke Alves   +12 more
wiley   +1 more source

Comparação dos achados da ultrassonografia transretal e resultados de biópsia na avaliação diagnóstica do câncer de próstata. [PDF]

, 2002
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Tavares, Yan Schaefer
core  

Evaluating the Impact of Age on Prostate Cancer Overdiagnosis Using Long‐Term Follow‐Up From the CAP Randomised Trial

International Journal of Cancer, EarlyView.
Uncertainty persists over whether the benefits of prostate‐specific antigen (PSA) screening outweigh harms from overdiagnosis, a key barrier to population‐wide adoption. Here, English male mortality rates were analyzed alongside long‐term data from the UK Cluster Randomized Trial of PSA Testing for Prostate Cancer (CAP) to estimate age‐specific ...
Adam R. Brentnall, Matejka Rebolj, Peter Sasieni, Garth Funston, Rhian Gabe, Andrew J. Vickers   +5 more
wiley   +1 more source

Prostate health index (phi) and prostate cancer antigen 3 (PCA3) significantly improve diagnostic accuracy in patients undergoing prostate biopsy

, 2012
BACKGROUND: Prostate health index (phi) and prostate cancer antigen 3 (PCA3) have been recently proposed as novel biomarkers for prostate cancer (PCa).
Longo M, De Sio M, Damiano R, ALTIERI, Vincenzo, AUTORINO, Riccardo, Perdonà, S, Bruzzese D, Perruolo G, Mazzarella C, Oliva A, Perdonà S, Altieri V, DE SIO, Marco, Ferro M, Autorino R, Marino A, Di Lorenzo G, OLIVA, Adriana, Terracciano D., Spinelli R   +19 more
core   +1 more source

Prognostic Value of Perioperative Anemia in Neurosurgical‐Oncological Treatment of Spinal Metastases

International Journal of Cancer, EarlyView.
High perioperative morbidity in patients undergoing surgery for spinal metastases highlights the need to identify modifiable risk factors, particularly the underexplored role of anemia. This study assessed associations between perioperative hemoglobin levels and complications, recurrence, and mortality in patients treated surgically for spinal ...
Marija Janjic, Logman Khalafov, Juliane Dittmer, Saif‐Eldin Abedellatif, Tim Lampmann, Harun Asoglu, Mohammed Jaber, Haitham Alenezi, Muriel Heimann, Matthias Schneider, Motaz Hamed, Marcus Thudium, Hartmut Vatter, Mohammed Banat   +13 more
wiley   +1 more source

Pain Control and Its Relationship with Histopathological Outcome in TRUS-Guided Prostate Needle Biopsy: A Prospective Non-Randomized Trial

, 2015
Objective Transrectal ultrasound-guided prostate biopsy (TRUS-Bx) is a standard diagnostic modality for detecting prostate cancer (PCa). Pain during biopsy is the most important problem that still needs a solution.
Tufan Tarcan, Aslan Demir, Kürşat Çeçen, Mert Ali Karadağ   +3 more
core   +1 more source

Prevalence of Helicobacter pylori Exposure and Risk Factors Among BRCA1 and BRCA2 Carriers

International Journal of Cancer, EarlyView.
BRCA1 and BRCA2 pathogenic germline variant (PGV) carriers may be at increased risk of gastric cancer (GC), especially in the case of prior or active Helicobacter pylori (Hp) infection. The extent to which Hp influences BRCA1 and BRCA2‐associated GC remains uncertain. Here, the authors evaluated plasma samples from a U.S. cohort of BRCA1, BRCA2, PALB2,
Kole H. Buckley, Yuhan Zhu, Kevin Dinh, Ryan Hausler, Rohan Gala, Sophia R. Spiegel, Rosella Delgado, Daniel G. Clay, Gregory M. Kelly, Jamie Brower, Susan M. Domchek, Kara N. Maxwell, Bryson W. Katona   +12 more
wiley   +1 more source

Relação do antígeno prostático específico, escore do gleason e da percentagem de tumor na biópsia com estadiamento patológico no câncer de próstata. [PDF]

, 2006
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Pilau, Nicole Morem
core