Results 81 to 90 of about 576,362 (247)

History of prostate biopsy – part 2

, 2018
The major limitations of the transrectal ultrasound (TRUS) guided prostate biopsy (PBx) protocols are the risk of profound sepsis and the risk of persistently significant false negative rates, related to the under sampling of the anterior and apical ...
Oussama Elhage, Mohamed Hammadeh, Ben Challacombe, Rick Popert, Sanjeev Madaan, Shiv Kumar Pandian   +5 more
core  

Body mass index is not a predictor of biochemical recurrence after radical prostatectomy in Dutch men diagnosed with prostate cancer [PDF]

, 2010
Contains fulltext : 95677.pdf (Publisher’s version ) (Open Access)PURPOSE: To determine the effect of body mass index (BMI) on clinical and pathological characteristics at time of diagnosis and on risk of biochemical recurrence after ...
van Roermond, J.G., Herbert F. M. Karthaus, Roermund, J.G.H. van, Aben, Katja K., Luijtgaarden, M.W. van de, van Roermund, Joep G. H., Kampman, Ellen, Kok, D.E.G., J. Alfred Witjes, Kiemeney, L.A.L.M., Oncko B. van Vierssen Trip, Kiemeney, L.A., Vierssen Trip, O.B., van, Katja K. Aben, Ellen Kampman, Aben, K.K.H., Luijtgaarden, M.W., van de, Lambertus A. L. M. Kiemeney, van Vierssen Trip, O.B., van de Luijtgaarden, M.W., van Vierssen Trip, Oncko B., Vierssen Trip, O. van, Roermond, J.G., van, Kok, Dieuwertje E. G., van de Luijtgaarden, Moniek W. M., Joep G. H. van Roermund, Kok, D.E., Moniek W. M. van de Luijtgaarden, Aben, K.K., Kampman, E., Karthaus, Herbert F. M., Alfred Witjes, J., Karthaus, H.F.M., Kiemeney, Lambertus A. L. M., Witjes, A.J., Witjes, J.A., Dieuwertje E. G. Kok, Karthaus, H.F.   +37 more
core   +2 more sources

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source

Clinical value of transrectal ultrasonography-guided biopsy combined with complexed prostate-specific antigen detection in diagnosis of prostate cancer

肿瘤影像学, 2015
      Objective: To evaluate the clinical value of transrectal ultrasonography (TRUS)-guided 10-core plus fixed-point prostate biopsy combined with complexed prostate-specific antigen (cPSA) detection in the diagnosis of prostate
ZHU Xueping, ZHANG Lijie, CHEN Yanjun, ZHU Qianxiong, MAO Jinyu, DING He, GENG He, ZHANG Tao, YUAN Ya, ZHANG Yuna, HU Haiqiang   +10 more
doaj  

Impact of Prostate Needle Biopsy on Erectile Function [PDF]

, 2019
Aim:To evaluate the impact of transrectal ultrasonography-guided prostate needle biopsy (TRUS-Bx) on erectile function.Methods:Patients who underwent TRUS-Bx were prospectively examined.
Ömer Sarılar, Ali Ayrancı, Fatih Yanaral, Faruk Özgör, Metin Savun, Alkan Çubuk, Ufuk Çağlar   +6 more
core   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

Advanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Targeted Prostate Biopsy: How, When, and Why? A Systematic Review

Diagnostics
Objective: Prostate cancer, the second most diagnosed cancer among men, requires precise diagnostic techniques to ensure effective treatment. This review explores the technological advancements, optimal application conditions, and benefits of targeted ...
Giacomo Rebez, Maria Barbiero, Franco Alchiede Simonato, Francesco Claps, Salvatore Siracusano, Rosa Giaimo, Gabriele Tulone, Fabio Vianello, Alchiede Simonato, Nicola Pavan   +9 more
doaj   +1 more source

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

The transverse and vertical distribution of prostate cancer in biopsy and radical prostatectomy specimens

BMC Cancer, 2018
Background Prostate biopsy is the most common method for the diagnosis of prostate cancer and the basis for further treatment. Confirmation using radical prostatectomy specimens is the most reliable method for verifying the accuracy of template-guided ...
Zhipeng Mai, Zhien Zhou, Weigang Yan, Yu Xiao, Yi Zhou, Zhiyong Liang, Zhigang Ji, Hanzhong Li   +7 more
doaj   +1 more source