Results 61 to 70 of about 105,659 (312)

External validation of extended prostate biopsy nomogram [PDF]

, 2015
Introduction Historical nomograms for the prediction of cancer on prostate biopsy, developed in the sex- tant biopsy era are no more accurate today. The aim of this study was an independent external validation of a 10-core biopsy nomogram by Chun et al.
Sieger T., Minárik I., Babjuk M., Hrbáček J.   +3 more
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Hair embedding after transperineal prostate biopsy: two case reports

BMC Urology, 2023
Background Transperineal prostate biopsy is gradually becoming the standard methodology for diagnosing prostate cancer because of its high accuracy and low risk of infection, but careful preparation is not always highlighted before a transperineal biopsy.
Jiaxuan Ni, Ying Ni, Tielong Zhang, Gang Wang, Xuefei Ding, Guangchen Zhou   +5 more
doaj   +1 more source

Systematic and MRI-Cognitive Targeted Transperineal Prostate Biopsy Accuracy in Detecting Clinically Significant Prostate Cancer after Previous Negative Biopsy and Persisting Suspicion of Malignancy

Medicina, 2021
Background and objectives: Overdiagnosis, overtreatment, and the need for repeated procedures caused by transrectal ultrasound guided prostate biopsies and their related complications places a heavy burden on healthcare systems.
Alvydas Vėželis, Gediminas Platkevičius, Marius Kinčius, Liutauras Gumbys, Ieva Naruševičiūtė, Rūta Briedienė, Donatas Petroška, Albertas Ulys, Feliksas Jankevičius   +8 more
doaj   +1 more source

A new ASAP Scoring System and Risk Table to predict second prostate biopsy outcomes

, 2021
Introduction This study aimed to discuss the necessity of a second prostate biopsy in patients with atypical small acinar proliferation (ASAP) and to develop a scoring system and risk table to be used as new criteria for a second biopsy.
Akan Serkan, Kaya Neslihan, Ihvan Aysenur, Ediz Caner   +3 more
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Body mass index is not a predictor of biochemical recurrence after radical prostatectomy in Dutch men diagnosed with prostate cancer [PDF]

, 2010
Contains fulltext : 95677.pdf (Publisher’s version ) (Open Access)PURPOSE: To determine the effect of body mass index (BMI) on clinical and pathological characteristics at time of diagnosis and on risk of biochemical recurrence after ...
van Roermond, J.G., Herbert F. M. Karthaus, Roermund, J.G.H. van, Aben, Katja K., Luijtgaarden, M.W. van de, van Roermund, Joep G. H., Kampman, Ellen, Kok, D.E.G., J. Alfred Witjes, Kiemeney, L.A.L.M., Oncko B. van Vierssen Trip, Kiemeney, L.A., Vierssen Trip, O.B., van, Katja K. Aben, Ellen Kampman, Aben, K.K.H., Luijtgaarden, M.W., van de, Lambertus A. L. M. Kiemeney, van Vierssen Trip, O.B., van de Luijtgaarden, M.W., van Vierssen Trip, Oncko B., Vierssen Trip, O. van, Roermond, J.G., van, Kok, Dieuwertje E. G., van de Luijtgaarden, Moniek W. M., Joep G. H. van Roermund, Kok, D.E., Moniek W. M. van de Luijtgaarden, Aben, K.K., Kampman, E., Karthaus, Herbert F. M., Alfred Witjes, J., Karthaus, H.F.M., Kiemeney, Lambertus A. L. M., Witjes, A.J., Witjes, J.A., Dieuwertje E. G. Kok, Karthaus, H.F.   +37 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Molecular Profiling of Prostate Cancer Patients [PDF]

, 2009
In the UK, more than 30 000 men are diagnosed annually with prostate cancer (PCa) and about 10 000 men die from it each year. Although several molecular markers have been associated with prostate cancer development and/ or progression, only few of them
Nna, Emmanuel Okechukwu
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source