Results 41 to 50 of about 163,352 (307)

Negative multiparametric magnetic resonance imaging for prostate cancer: what's next? [PDF]

, 2018
Multiparametric magnetic resonance imaging (mpMRI) of the prostate has excellent sensitivity in detecting clinically significant prostate cancer (csPCa).
Barchetti, Flavio, Barchetti, Giovanni, Campa, Riccardo, Catalano, Carlo, Ciardi, Antonio, Del Monte, Maurizio, Gallucci, Michele, Grompone, Marcello Domenico, Indino, ELENA LUCIA, Leonardo, Costantino, Panebianco, Valeria, Sciarra, Alessandro, Simone, Giuseppe   +12 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Prostate cancer treatment with Irreversible Electroporation (IRE): Safety, efficacy and clinical experience in 471 treatments. [PDF]

, 2019
BackgroundIrreversible Electroporation (IRE) is a novel image-guided tissue ablation technology that induces cell death via very short but strong pulsed electric fields.
Guenther, E, Klein, N, Rubinsky, B, Schlosser, C, Stehling, MK, Weil, S, Zapf, S   +6 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Magnetic resonance imaging for localization of prostate cancer in the setting of biochemical recurrence [PDF]

, 2016
The clinical suspicion of local recurrence of prostate cancer after radical treatment is based on the onset of biochemical failure. The use of multiparametric magnetic resonance imaging (MRI) for prostate cancer has increased over recent years, mainly ...
Barchetti, Flavio, Cardone, Gianpiero, Catalano, Carlo, Colarieti, Anna, Grompone, Marcello Domenico, Panebianco, Valeria, Salvo, Vincenzo   +6 more
core   +1 more source

Optimizing prostate biopsy techniques [PDF]

Current Opinion in Urology, 2019
Prostate cancer (PCa) diagnostics have undergone a number of changes as a result of efforts to reduce the detection rate of indolent prostate cancer and to increase the hit rate for clinically significant prostate cancer (csPCa). Here, we look at those studies that have shifted our knowledge and the impact these have had on clinical practice.The ...
Altan, Omer, Alastair D, Lamb
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A review of optimal prostate biopsy: indications and techniques

Therapeutic Advances in Urology, 2019
Prostate biopsy is the gold standard diagnostic technique for the detection of prostate cancer. Patient selection for prostate biopsy is complex and is influenced by emerging use of prebiopsy imaging.
Justin Streicher, Brian Lee Meyerson, Vidhya Karivedu, Abhinav Sidana   +3 more
doaj   +1 more source

Transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume: 103 cases requiring repeat prostate biopsy

BMC Urology, 2017
Background We evaluated the cancer detection rate of prostate cancer using transperineal template-guided saturation biopsy aimed at sampling one core for each milliliter of prostate volume for patients requiring repeated prostate biopsies.
Yasushi Nakai, Nobumichi Tanaka, Satoshi Anai, Makito Miyake, Shunta Hori, Yoshihiro Tatsumi, Yosuke Morizawa, Tomomi Fujii, Noboru Konishi, Kiyohide Fujimoto   +9 more
doaj   +1 more source

Hair embedding after transperineal prostate biopsy: two case reports

BMC Urology, 2023
Background Transperineal prostate biopsy is gradually becoming the standard methodology for diagnosing prostate cancer because of its high accuracy and low risk of infection, but careful preparation is not always highlighted before a transperineal biopsy.
Jiaxuan Ni, Ying Ni, Tielong Zhang, Gang Wang, Xuefei Ding, Guangchen Zhou   +5 more
doaj   +1 more source