Results 51 to 60 of about 576,362 (247)

Hair embedding after transperineal prostate biopsy: two case reports

BMC Urology, 2023
Background Transperineal prostate biopsy is gradually becoming the standard methodology for diagnosing prostate cancer because of its high accuracy and low risk of infection, but careful preparation is not always highlighted before a transperineal biopsy.
Jiaxuan Ni, Ying Ni, Tielong Zhang, Gang Wang, Xuefei Ding, Guangchen Zhou   +5 more
doaj   +1 more source

Systematic and MRI-Cognitive Targeted Transperineal Prostate Biopsy Accuracy in Detecting Clinically Significant Prostate Cancer after Previous Negative Biopsy and Persisting Suspicion of Malignancy

Medicina, 2021
Background and objectives: Overdiagnosis, overtreatment, and the need for repeated procedures caused by transrectal ultrasound guided prostate biopsies and their related complications places a heavy burden on healthcare systems.
Alvydas Vėželis, Gediminas Platkevičius, Marius Kinčius, Liutauras Gumbys, Ieva Naruševičiūtė, Rūta Briedienė, Donatas Petroška, Albertas Ulys, Feliksas Jankevičius   +8 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

EVALUATION OF THE EFFECTIVENESS OF MULTIFOCAL PUNCTURE BIOPSY IN THE DIAGNOSIS OF PROSTATE CANCER

Клінічна та профілактична медицина
Introduction. The value of multifocal puncture biopsy of the prostate is undoubtedly extremely important today for the timely diagnosis of prostate cancer.
Mykola D. Sosnin, Volodymyr O. Shaprynskyi, Viktor I. Gorovyi, Oleh M. Kapshuk, Volodymyr V. Danylko, Mykhailo A. Verba   +5 more
doaj   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Effect of Finasteride on PSA and Histopathological Results in Patients Undergoing Prostate Biopsy

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2022
Introduction: Prostate cancer management focuses on rapid diagnosis and treatment. The present study was performed to investigate the effect of finasteride on PSA changes and biopsy results.
Saman Farshid, Ali Tehranchi, Amir Jamei, Faramarz Ojaghi, Farid Kalashipour   +4 more
doaj  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Analysis of the cause of missed diagnosis in mpMRI/TRUS fusion-guided targeted prostate biopsy

BMC Urology, 2022
Objectives To investigate the causes of missed diagnosis in mpMRI/TRUS fusion-guided targeted prostate biopsy. Methods The clinical data of 759 patients who underwent transperineal prostate biopsy from March 2021 to June 2021 at Nanjing DrumTower ...
Fan Zhang, Shun Zhang, Haifeng Huang, Qing Zhang, Shengjie Zhang, Shiwei Zhang, Hongqian Guo   +6 more
doaj   +1 more source

Роль и значение мультипараметрической магнитно-резонансной томографии в диагностике рака предстательной железы [PDF]

, 2017
The problem of timely diagnosis and malignancy grade evaluation of prostate cancer is especially urgent considering continuous and progredient increase in morbidity and mortality caused by this nosology, as well as difficulty of diagnostics.
I. E. Turin, Б. Ш. Камолов, Ю. В. Буйденок, В. Б. Матвеев, B. Sh. Kamolov, G. I. Akhverdieva, И. И. Абдуллин, В. О. Панов, V. B. Matveev, V. A. Chernyaev, V. O. Panov, Yu. V. Buydenok, В. А. Черняев, И. Е. Тюрин, Ph. A. Kossov, I. I. Abdullin, Ф. А. Коссов, Г. И. Ахвердиева   +17 more
core   +4 more sources

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source