Results 141 to 150 of about 8,267,805 (249)

Loss of Twist1 leads to disruption of ciliary length, endocytic vesicle dynamics, and cell–cell junctions during neural tube formation

Developmental Dynamics, EarlyView.
Abstract Background Endocytosis constitutes a fundamental cellular process governing development through coordinated regulation of plasma membrane remodeling and ciliogenesis, processes essential for cell shape changes and tissue development. Although Twist1 null embryos display complete cranial neural tube (NT) closure defects and conditional knockout
Derrick Thomas, Brittany M. Hufft‐Martinez, Zarna Lalwani, Vi Pham, Mary Elmeniawi, An J. Tran, Jianming Xu, Irfan Saadi, Walid D. Fakhouri   +8 more
wiley   +1 more source

Genomic and transcriptomic correlates of deep prostate-specific antigen response in patients with metastatic androgen pathway modulation-sensitive prostate cancer. [PDF]

Oncologist
McKay RR, Kilari D, Yilma B, Jariwala U, Ashok A, Fragkogianni S, Mercer J, Agarwal N, Antonarakis ES.   +8 more
europepmc   +1 more source

Use of prostate specific antigen. A review

, 1998
Since it was first introduced, measurement of prostate specific antigen has gained increasing interest, and prostate specific antigen is regarded as being the best tumour marker available.
Skaarup, P, Iversen, Peter, Brasso, K, Roosen, Jens Ulrik   +3 more
core  

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

Electron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary, Harsh Sable, Sonu Sonu, Lakshita Phor, Reddicherla Umapathi, Pradeep Bhadola   +5 more
wiley   +1 more source

Development and evaluation of a novel experimental autoimmune prostatitis model induced by a prostate-specific antigen mixture in rats. [PDF]

Biochem Biophys Rep
Hong X, Hong T, Liu X, Lin S, Chi Z, Liu G, Lin W, Zhang Y.   +7 more
europepmc   +1 more source

The ongoing dilemma of immunotherapy in antibody‐negative suspected autoimmune encephalitis‐associated epilepsy: A retrospective cohort study

Epileptic Disorders, EarlyView.
Abstract Objectives This study evaluates immunotherapy in drug‐resistant epilepsy (DRE) patients with concern for autoimmune encephalitis‐associated epilepsy (AEAE) but negative neural antibody testing (−Ab). Methods A retrospective cohort study, focusing on patients treated at our Epilepsy Monitoring Unit (EMU) from January 2018 to May 2022.
Norah A. ALKhaldi, Hellen Kreinter, Jorge G. Burneo, Michelle‐Lee Jones, Adrian Budhram, Ana Suller Marti   +5 more
wiley   +1 more source

Next‐Generation CAR‐T Cell Therapy: From Modular Design to Clinical Expansion

Exploration, EarlyView.
Over the past decades, chimeric antigen receptor (CAR)‐T cell therapy has evolved from a linear engineering concept into a powerful yet constrained immunotherapy, limited by tumour microenvironment barriers, immune evasion, and manufacturing complexity.
Yuesong Bai, Jintao Qin, Zongjun Dai, Ran Yan, Yong Yang, Wenguang Wang   +5 more
wiley   +1 more source

Postoperative prostate-specific antigen kinetics after holmium laser enucleation of the prostate in men with low-risk prostate cancer. [PDF]

BJUI Compass
Bakbak H, Singh G, Abdelaziz A, Velasquez Ospina J, Resnik S, Nee CS, Khandekar A, Katz JE, Punnen S, Marcovich R, Gonzalgo ML, Parekh DJ, Shah HN.   +12 more
europepmc   +1 more source

A Nitric Oxide–Based STING Agonist Nanoadjuvant With ICD‐Derived Membrane Antigens Unleashes Robust Antitumor Immunity

Exploration, EarlyView.
Schematic illustration of the synergistic antitumor mechanism of Im@NOnanoPL combined with αPD‐1 therapy. The Im@NOnanoPL nanovaccine targets lymph nodes via ICD‐derived tumor cell membranes, delivering personalized tumor antigens. It releases NO gas to enhance MHC‐I expression and activate the STING pathway, thereby potentiating anti‐tumor immunity in
Shuyu Xu, Yang Song, Tianjiao Zhang, Yan Wang, Mengxin Wang, Xinxin Xie, Qingfeng Chen, Xiaolong Liang   +7 more
wiley   +1 more source

Complementary detection of clinically significant prostate cancer by magnetic resonance imaging fusion-targeted and systematic transrectal ultrasound-guided biopsy: influence of prostate-specific antigen and prostate-specific antigen density in a retrospective paired cohort. [PDF]

Prostate Int
Visuthikosol T, Viseshsindh W.
europepmc   +1 more source