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Prostate-specific antigen vaccines for prostate cancer
Expert Opinion on Biological Therapy, 2002Prostate cancer is the most common malignant tumour in men and there are few treatment options available once the tumour becomes refractory to hormonal manipulation. Prostate-specific antigen (PSA) is a secretory glycoprotein that is commonly expressed by prostatic epithelial cells and is found in elevated levels in the serum of men with prostate ...
Heidi, Hörig +2 more
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Evaluation of Prostate-Specific Antigen in Prostate Cancer
American Journal of Clinical Oncology, 1988Prostate-specific antigen (PSA) was assayed retrospectively in 131 prostate cancer patients. Pretreatment levels at primary tumor diagnosis were above 5 ng/ml in 13/16 (81%) of stage B and C patients and in 28/28 (100%) of stage D (D1 and D2) patients.
D, Pons-Anicet +3 more
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Prostatic intraepithelial neoplasia and prostate-specific antigen
World Journal of Urology, 1993Prostatic intraepithelial neoplasia (PIN) is a putative premalignant lesion of the prostate gland. PIN has been demonstrated to share morphologic and phenotypic similarities to invasive carcinoma of the prostate. In addition, PIN is spatially related to invasive carcinoma and occurs with greater frequency in men whose prostates harbor carcinoma ...
J R, Porter, M K, Brawer
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Prostate-specific antigen in management of prostatic carcinoma
Urology, 1989In 1979, Wang and associates isolated prostate-specific antigen (PSA). Only recently, however, has the clinical importance of this new tumor marker been recognized. It is now widely accepted that PSA represents a significantly more effective tumor marker than prostatic acid phosphatase (PAP).
M K, Brawer, P H, Lange
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Screening for Prostatic Carcinoma with Prostate Specific Antigen
Journal of Urology, 1992Prostate specific antigen (PSA), neutral serine protease secreted exclusively by prostatic epithelial cells, has a number of applications in the management of men with prostatic carcinoma. While it is widely recognized that elevated PSA correlates with the presence of carcinoma, little data exist regarding the use of PSA as the initial test in the ...
M K, Brawer +5 more
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Prostate-specific antigen as a marker of prostate disease
Virchows Archiv, 2000Serum prostate markers, in particular prostate-specific antigen (PSA), have truly revolutionised all aspects of the management of men with prostatic carcinoma (PCa), the most important application being related to its early detection and screening. Several studies have shown the clinical utility of PSA levels for staging patients with PCa, especially ...
R, Montironi +4 more
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Prostate cancer in the era of prostate-specific antigen
Current Opinion in Oncology, 1995The number of cases of prostate cancer diagnosed increased by 15% in the past year. This trend is likely to continue as prostate-specific antigen testing was approved for screening during the past year. The result is that mroe patients are being diagnosed at an earlier and presumably curable stage, although the long-term impact on survival has not been
H I, Scher, S, Fossa
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Prostate‐specific membrane antigen
British Journal of Urology, 1998B H, Maraj, P, Whelan, A F, Markham
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