Results 41 to 50 of about 8,267,805 (249)

The Value of Prostate-Specific Antigen-Related Indexes and Imaging Screening in the Diagnosis of Prostate Cancer

open access: yesCancer Management and Research, 2020
Xiaojing Bai,1,2,* Yumei Jiang,1,2,* Xinwei Zhang,1,2 Meiyu Wang,3 Juanhua Tian,1 Lijun Mu,1 Yuefeng Du1,2 1Department of Urology, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710061, People’s Republic of ...
Bai X   +6 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Correlation Between Prostate-Specific Antigen Density and Findings from Multiparametric Magnetic Resonance Imaging of Prostate

open access: yesCerrahpaşa Medical Journal, 2022
Objective: The present study is intended to investigate the relationship between multiparametric prostate magnetic resonance findings and prostatespecific antigen density in the diagnosis of prostate cancer.
Cansu Öztürk   +3 more
doaj   +1 more source

Investigation of prostate specific antigen glycosylation [PDF]

open access: yesJournal of the Serbian Chemical Society, 2000
In the present work, prostate specific antigen (PSA) glycosylation was examined by lectin affinity methods. The results obtained indicated that PSA purified from human seminal plasma contained at least one bianntenary N-linked oligosaccharide ...
Marinović Vesna, Čuperlović Margita
doaj   +3 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Digital rectal examination (DRE) does not influence total serum levels of prostate specific antigen (tPSA), in individuals without prostate pathology

open access: yesInternational Brazilian Journal of Urology, 2003
OBJECTIVE: To evaluate if the digital rectal examination (DRE) performed before determination of total serum prostate specific antigen (tPSA) influences the levels of this protein.
Maria de F. Figueirêdo   +2 more
doaj   +1 more source

Development of prostrate cancer vaccine using PAP as target antigen [PDF]

open access: yes, 2014
Treatment options for patients with advanced prostate cancer (PC) still remain limited and rarely curative. The prostatic acid phosphatase (PAP) is prostate specific protein over-expressed in more than 90% of prostate tumours.
Javad, JMS
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Correlation of Serum Gamma Glutamyl Transferase and Prostate Specific Antigen Level in Patients with Prostate Disorders

open access: yesPakistan Armed Forces Medical Journal
Objective: To correlate gamma-glutamyl transferase, prostate-specific antigen, and prostate-specific antigen density with ultrasound findings, including prostate-specific antigen volume and density, in patients with prostate disorders and to compare ...
Mehreen Aftab Khan   +5 more
doaj   +1 more source

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