Results 31 to 40 of about 258,151 (309)

Tyrol Prostate Cancer Demonstration Project : early detection, treatment, outcome, incidence and mortality

, 2008
This study aimed to evaluate the effectiveness of a well-controlled programme of early detection and treatment of prostate cancer in the population of Tyrol, Austria, where such a programme of early detection and treatment was initiated in 1988 and where
Severi, Gianluca, Frauscher, Ferdinand, Horninger, Wolfgang, Klocker, Helmut, Schennach, Harald, Tyrol Prostate Canc Screening Grp, Boniol, Mathieu, , Tyrol Prostate Canc Screening Grp, Bektic, Jasmin, Boyle, Peter, Robertson, Chris, Pelzer, Alexandre, Oberaigner, Wilhelm, Schafer, Georg, Bartsch, Georg   +14 more
core   +1 more source

Prostate specific antigen criteria to diagnose failure of cancer control following focal therapy of nonmetastatic prostate cancer using high Intensity focused ultrasound [PDF]

, 2020
PURPOSE: We determined whether prostate specific antigen criteria after focal high intensity focused ultrasound to treat prostate cancer could diagnose treatment failure.
Persad, Raj, Hosking-Jervis, Feargus, Huber, Philipp Markus, Afzal, N, Odgen, C, Persad, R, Moore, CM, Afzal, Naveed, Ahmed, Hashim U, Huber, PM, Thalmann, George N, Guillaumier, S, Boxler, S, Nigam, R, Emberton, M, Hindley, RG, Huber, Philipp M, Leemann, Lucas, Hosking-Jervis, F, Emberton, Mark, Winkler, M, Dudderidge, T, Virdi, Jaspal, Virdi, J, Hindley, Richard G, Lewi, Henry, Moore, Caroline M, Boxler, Silvan, Dudderidge, Tim, Leemann, L, McCartan, Neil, Odgen, Chris, Guillaumier, Stephanie, Nigam, Raj, Arya, Manit, Winkler, Mathias, Arya, M, Ahmed, HU, Thalmann, GN, Lewi, H, McCartan, N, Thalmann, George   +41 more
core   +1 more source

Biology of prostate-specific antigen

Urology, 2003
The human kallikrein (hk) family, located on chromosome 19, encodes prostate-specific antigen (PSA [or hK3]), hK2, hK4, and hK15 (prostin), as well as other serine proteases. Although PSA has been used in the detection of prostate cancer for several years, much remains unknown about its function and forms.
Steven P, Balk, Yoo-Joung, Ko, Glenn J, Bubley   +2 more
openaire   +6 more sources

Prostate Specific Antigen: A review [PDF]

Acta Oncologica, 1991
Despite its identification in the 1970s, prostate specific antigen (PSA) has only recently gained widespread utility. In this review, we will describe significant aspects of the biochemistry of PSA, immunohistochemical applications, the effect of prostatic manipulation on the serum level of this analyte, and other considerations in the determination of
openaire   +2 more sources

Socio-economic inequalities in survival of patients with prostate cancer: role of age and Gleason grade at diagnosis [PDF]

, 2013
In the United Kingdom, survival of prostate cancer patients has improved since the 1990s. A deprivation gap in survival (better survival for the least deprived compared with the most deprived) has been reported but it is not known if differential ...
Morrison David S., Morrison, D., David S Morrison, Shafique Kashif, Shafique, M., Kashif Shafique   +5 more
core   +1 more source

Investigation of prostate specific antigen glycosylation [PDF]

Journal of the Serbian Chemical Society, 2000
In the present work, prostate specific antigen (PSA) glycosylation was examined by lectin affinity methods. The results obtained indicated that PSA purified from human seminal plasma contained at least one bianntenary N-linked oligosaccharide ...
Marinović Vesna, Čuperlović Margita
doaj   +3 more sources

ASSOCIATION OF OBESITY AND DIABETES WITH SERUM PROSTATE-SPECIFIC ANTIGEN LEVELS IN JAPANESE MALES [PDF]

, 2012
2012-08Patients with diabetes have been reported to be at an increased risk for cancers of the pancreas, liver, and colon; however, recent studies have suggested that men with diabetes are at a decreased risk for prostate cancer.
ASAI, YATAMI, MORITA, EMI, NISHIO, KAZUKO, HAMAJIMA, NOBUYUKI, WAKAI, KENJI, MORI, ATSUYOSHI, TAMAKOSHI, AKIKO, HISHIDA, ASAHI, KATASE, SHIRO, OKADA, RIEKO, NAITO, MARIKO, FUKADA, YUKO, KAWAI, SAYO, KUWABARA, MAYUMI   +13 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Development of a sensitive detection method of cancer biomarkers in human serum (75%) using a quartz crystal microbalance sensor and nanoparticles amplification system [PDF]

, 2010
A simple and sensitive sensor method for cancer biomarkers [prostate specific antigen (PSA) and PSA-alpha 1-antichymotrypsin (ACT) complex] analysis was developed, to be applied directly with human serum (75%) by using antibody modified quartz crystal
Uludag, Yildiz, Tothill, Ibtisam E.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source