Results 101 to 110 of about 87,487 (309)
Med Research, EarlyView.ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin +8 more
wiley +1 more source
Management of lower urinary tract symptoms in men : summary of NICE guidance [PDF]
, 2010 Peer reviewedPublisher ...
Chapple, Christopher +4 more
core +2 more sources
Acta Clinica Croatica, 2018 Prostatic artery embolization is a minimally invasive endovascular treatment that improves lower urinary tract symptoms in men with benign prostatic hyperplasia.
Luka Novosel +4 more
doaj +1 more source
The Journal of Pathology, EarlyView.Abstract Although relatively rare, metaplastic breast cancer responds poorly to traditional therapies compared to other subtypes. Accordingly, there is a need for novel animal models to understand its pathogenesis and plasticity. Since alterations in PIK3CA and TP53 genes are common in metaplastic breast cancer, we generated a mouse model of ...
Khoa A Nguyen +11 more
wiley +1 more source
A brief review of the literature on the malignant ureteral obstruction [PDF]
, 2018 Malignant ureteral obstruction (MUO) caused by a primarily urological tumor or secondary to a late-stage malignancy can be difficult for the urologist to manage. Due to a lack of clinical data on the management of MUO, every case is particular and should
Brînză, Adrian +7 more
core +1 more source
Сибирский онкологический журнал, 2018 Introduction. The transcription factor Brn-3α (product of the POU4F1) plays a significant role in carcinogenesis. The purpose of the study was to investigate Brn-3α, AR, ERα expressions in tissues of benign prostatic hyperplasia and prostate cancer as ...
L. V. Spirina +4 more
doaj +1 more source
Altered Glycosylation of PSA in Prostate Cancer Tissue
The Prostate, EarlyView.ABSTRACT Background The glycosylation of proteins is commonly altered in cancer. This offers novel opportunities for cancer biomarker development. As prostate‐specific antigen (PSA) is a glycoprotein, identification of cancer‐specific PSA‐glycoforms is feasible. Such PSA‐glycoforms may provide valuable diagnostic and prognostic information. Methods PSA‐
Hannu Koistinen +7 more
wiley +1 more source
Improving Patient Decision-Making in Health Care [PDF]
, 2011 Outlines regional variations within Minnesota in rates of patients with similar conditions receiving elective surgery, the concept of shared decision making, treatment choices for eight conditions, and steps for ensuring patients make informed ...
David C. Goodman +5 more
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Is There Any Association Between Periodontitis and Prostatic Alterations? A Systematic Review
The Prostate, EarlyView.ABSTRACT Background The prostate plays a crucial role in male reproduction but is susceptible to diseases such as prostate cancer. Periodontitis, as an inflammatory disease, has the potential to modulate systemic conditions. This systematic review aimed to evaluate the association between periodontitis and prostatic alterations.
Beatriz Rodrigues Risuenho Peinado +11 more
wiley +1 more source
Patient Related Outcome Measures, 2011 Bob Djavan, Seyed Saeid Dianat, Amir KazzaziNew York University, Department of Urology, New York, USABackground: Benign prostatic hyperplasia, the fourth most commonly diagnosed medical condition in the elderly, is a major underlying cause of lower ...
Djavan B, Dianat SS, Kazzazi A
doaj