Results 101 to 110 of about 56,978 (262)

Psychogenic Urinary Frequency and the Role of Kampo Medicine: Addressing Limitations of SSRI Therapy in Panic Disorder

open access: yes
Traditional &Kampo Medicine, EarlyView.
Kazuyoshi Johnin   +4 more
wiley   +1 more source

Patient‐reported outcome measures in prostate research: a scoping review

open access: yesBJU International, EarlyView.
Objectives To summarise how patient‐reported outcome measures (PROMs) are used in prostate research, specifically in the 10 years after the 2010 CONsolidated Standards Of Reporting Trials (CONSORT) guidelines were introduced. Methods The search was focussed on randomised controlled trials (RCTs) reporting in the top 15 journals in oncology, urology ...
Grace J. Young   +6 more
wiley   +1 more source

New Therapies for Benign Prostatic Hyperplasia [PDF]

open access: bronze, 1992
Reginald C. Bruskewitz, Morten Riehmann
openalex   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz   +8 more
wiley   +1 more source

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

open access: yesCell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin   +9 more
wiley   +1 more source

CRISPR Technology in Disease Management: An Updated Review of Clinical Translation and Therapeutic Potential

open access: yesCell Proliferation, EarlyView.
CRISPR‐Cas systems offer transformative genome editing capabilities for precise manipulation of cellular genes. This enables two main therapeutic avenues: ex vivo modification of patient cells for re‐transplantation or direct in vivo gene targeting via advanced delivery methods.
Bahareh Farasati Far   +4 more
wiley   +1 more source

Is the Safety of Finasteride Correlated With Its Route of Administration: Topical Versus Oral? A Pharmacovigilance Study With Data From the United States Food and Drug Administration Adverse Event Reporting System

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Background The United States Food and Drug Administration (FDA) approved oral finasteride for androgenetic alopecia. In 2022, approximately 2.6 million U.S. men used it for hair loss and prostate conditions. Post‐finasteride syndrome (PFS), proposed in 2012, involves persistent sexual and neuropsychiatric adverse events (AEs) after cessation ...
Aditya K. Gupta   +3 more
wiley   +1 more source

Estimate Criteria for Diagnosis and Severity in Benign Prostatic Hyperplasia [PDF]

open access: bronze, 1996
Yukio Hornma   +10 more
openalex   +1 more source

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