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FDA expanded approval of Pluvicto (Lutetium-177 vipivotide tetraxetan) in metastatic castration-sensitive prostate cancer. [PDF]
Ann Med Surg (Lond)Saqib M, Arshad B, Imran SB, Haider E.
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Transrectal biplane ultrasound-guided transperineal biopsy for rectal and peri-rectal lesions: an 18-year retrospective analysis. [PDF]
Quant Imaging Med SurgOu D +12 more
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Ultrastructure of prostatic intraepithelial neoplasia
The Prostate, 1997Prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostatic adenocarcinoma. However, the ultrastructural features of PIN have not been defined in properly fixed tissues.In this study, we examined a total of 84 acini from 11 cases of high-grade PIN and matched benign epithelium and adenocarcinoma from patients undergoing radical ...
D G, Bostwick +2 more
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Prostatic Intraepithelial Neoplasia: An Update
Clinical Prostate Cancer, 2004High-grade prostatic intraepithelial neoplasia (HGPIN) is commonly encountered on prostate needle biopsies and, based on epidemiologic, molecular, and animal models, has proven to be the most significant risk factor for prostate cancer and likely represents the premalignant phase of prostatic adenocarcinoma.
Liang, Cheng +3 more
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Chemoprevention for Prostatic Intraepithelial Neoplasia
European Urology, 1996To evaluate the potential application of chemoprevention strategies in prostatic intraepithelial neoplasia.Review of relevant literature on chemoprevention with emphasis on prostate cancer and premalignant lesions.Chemoprevention represents a strategy designed to inhibit or reverse the process of carcinogenesis by administering one or several ...
P S, Nelson, T P, Gleason, M K, Brawer
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Clinical Evolution of Prostatic Intraepithelial Neoplasia
European Urology, 1999High-grade prostatic intraepithelial neoplasia (PIN) is most likely a precursor of prostate cancer and is frequently associated with it whereas the direct link between low-grade PIN and cancer is not established. The clinical evolution of isolated high-grade PIN has been the object of much concern because of the possibility of undiagnosed prostate ...
Zlotta, Alexandre, Schulman, Claude
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Prostatic Intraepithelial Neoplasia
Pathology Case Reviews, 2008Abstract:High-grade prostatic intraepithelial neoplasia (PIN) refers to the preinvasive end of the continuum of cellular proliferations within the lining of prostatic ducts, ductules, and acini. PIN is now accepted as the most likely preinvasive stage of adenocarcinoma, almost 2 decades after its ...
Rodolfo Montironi, Junqi Qian, Jun Ma
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Prostatic intraepithelial neoplasia
Current Urology Reports, 2000High-grade prostatic intraepithelial neoplasia (PIN) is now accepted as the most likely pre-invasive stage of adenocarcinoma, a decade after its first formal description. PIN has a high predictive value as a marker for adenocarcinoma, and its identification warrants repeat biopsy for concurrent or subsequent invasive carcinoma.
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Prostatic intraepithelial neoplasia and prostate-specific antigen
World Journal of Urology, 1993Prostatic intraepithelial neoplasia (PIN) is a putative premalignant lesion of the prostate gland. PIN has been demonstrated to share morphologic and phenotypic similarities to invasive carcinoma of the prostate. In addition, PIN is spatially related to invasive carcinoma and occurs with greater frequency in men whose prostates harbor carcinoma ...
J R, Porter, M K, Brawer
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