Results 211 to 220 of about 15,890 (255)

Patterns of Prostatic Intraepithelial Neoplasia

Electronic Journal of Pathology and Histology, 2001
High-grade prostatic intraepithelial neoplasia (PIN) is the most likely precursor of prostatic carcinoma. PIN has a high predictive value as a marker for carcinoma, and its identification in biopsy specimens warrants repeat biopsy for concurrent or subsequent carcinoma.
Roberta Mazzucchelli, Paola Colanzi, Roberto Pomante, Rodolfo Montironi   +3 more
openaire   +1 more source

PSA IN BENIGN PROSTATIC HYPERPLASIA AND PROSTATIC INTRAEPITHELIAL NEOPLASIA

Urologic Clinics of North America, 1993
Prostate specific antigen has become an important adjunct to the digital rectal examination in screening for prostate cancer. The clinician should be familiar with interpretation of this test. Many men with BPH have elevated serum PSA concentrations; however, the majority of these men will have other pathologic processes such as occult cancer, PIN, or ...
W J, Ellis, M K, Brawer
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Prostatic Adenocarcinoma, Prostatic Intraepithelial Neoplasia, and Intraductal Carcinoma

Surgical Pathology Clinics, 2008
Prostate carcinoma (PCa) exhibits a wide range of architectural and cytological features. Gleason grading remains as one of the most powerful histological prognostic parameters. However, it has evolved considerably. High-grade prostatic intraepithelial neoplasia (high-grade PIN) is accepted as a precursor lesion to PCa. Its detection in prostate biopsy
Ming, Zhou, Cristina, Magi-Galluzzi
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Prostatic Intraepithelial Neoplasia Occurs Spontaneously in the Canine Prostate

Journal of Urology, 1997
Prostatic intraepithelial neoplasia (PIN) is the most likely precursor of human prostate cancer. Although the dog is the only non-human species in which spontaneous prostate cancer occurs frequently, the prevalence of PIN in the canine prostate is unknown.
D J, Waters, D G, Bostwick
openaire   +2 more sources

Epidemiology of High-Grade Prostatic Intraepithelial Neoplasia

Scandinavian Journal of Urology and Nephrology, 2000
This review summarizes published data dealing with the prevalence of high-grade prostatic intraepithelial neoplasia (HGPIN) in a variety of prostate tissue samples. Additionally, we have attempted to document the relationship between HGPIN and the pathological parameters of prostate cancer in autopsy and radical prostatectomy specimens.
W A, Sakr, A, Billis, P, Ekman, T, Wilt, D G, Bostwick   +4 more
openaire   +2 more sources

Immunohistochemical Characterization of Canine Prostatic Intraepithelial Neoplasia

Journal of Comparative Pathology, 2010
The development of prostate cancer is believed to be a multistep process, progressing sequentially from normal epithelium, to prostatic intraepithelial neoplasia (PIN) and, finally, to invasive neoplasia. Malignant stem cells within the basal cell layer of the prostatic epithelium are believed to play an important role in the failure of androgen ...
P, Matsuzaki, B, Cogliati, D S, Sanches, L M, Chaible, K C, Kimura, T C, Silva, M A, Real-Lima, F J, Hernandez-Blazquez, R, Laufer-Amorim, M L Z, Dagli   +9 more
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Neuroendocrine Differentiation in Prostatic Intraepithelial Neoplasia and Adenocarcinoma

The American Journal of Surgical Pathology, 1994
Neuroendocrine cells are thought to have a regulatory role in prostatic epithelial growth and may be prognostically useful in prostatic adenocarcinoma. To determine the extent of neuroendocrine differentiation in high-grade prostatic intraepithelial neoplasia (PIN), a putative precursor of cancer, we studied the immunohistochemical expression of 10 ...
D G, Bostwick, M K, Dousa, B G, Crawford, P C, Wollan   +3 more
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Epidemology of High Grade Prostatic Intraepithelial Neoplasia

Pathology - Research and Practice, 1995
The prevalence of high grade prostatic intraepithelial neoplasia (HGPIN), the age at which this lesion starts and the potential racial or ethnic differences in its distribution are poorly documented. HGPIN is becoming increasingly implicated as a premalignant lesion for clinically significant prostatic carcinoma (PCa) with mounting evidence linking it ...
W A, Sakr, D J, Grignon, G P, Haas, K L, Schomer, L K, Heilbrun, B J, Cassin, J, Powell, J A, Montie, J E, Pontes, J D, Crissman   +9 more
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Prostatic intraepithelial neoplasia: Animal models 2000

The Prostate, 2000
Numerous animal models of preinvasive prostate cancer have been described in the past decade. Differences among models account for their variable applicability for answering specific research questions. The dog is the only known nonhuman spontaneous animal model of prostate cancer, but numerous transgenic and therapy-induced models have been generated ...
D G, Bostwick, D, Ramnani, J, Qian
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Age and Racial Distribution of Prostatic Intraepithelial Neoplasia

European Urology, 1996
To study the prevalence, extent and evolution of high-grade prostatic intraepithelial neoplasia (HGPIN) in African-American and Caucasian men of a wide age range in order to help clarify the role this lesion may play in the racial differences of prostate cancer.The lesion was documented in step-sectioned, entirely submitted prostates of two study ...
W A, Sakr, D J, Grignon, G P, Haas, L K, Heilbrun, J E, Pontes, J D, Crissman   +5 more
openaire   +2 more sources