Results 221 to 230 of about 15,890 (255)

Reversibility of Prostatic Intraepithelial Neoplasia: Implications for Chemoprevention

European Urology, 1999
High-grade prostatic intraepithelial neoplasia is the most likely precursor of prostatic adenocarcinoma, according to virtually all available evidence. It has a high predictive value as a marker for adenocarcinoma, and its identification in biopsy specimens of the prostate warrants further search for concurrent invasive carcinoma.
D G, Bostwick, R, Neumann, J, Qian, L, Cheng   +3 more
openaire   +2 more sources

[Prostatic intraepithelial neoplasia].

Annales de pathologie, 2001
Prostatic intraepithelial neoplasia (PIN) is the histologic lesion most strongly associated with prostate cancer and has been postulated to be a pre-malignant lesion. However, much of the natural history of PIN remains unknown. A more fundamental understanding of the relationship between PIN and invasive tumors at the molecular level is critically ...
openaire   +1 more source

Prostatic intraepithelial neoplasia and prostate cancer.

Panminerva medica, 2002
Prostatic intraepithelial neoplasia (PIN) is composed of dysplastic cells with a luminal cell phenotype, expressing the androgen receptor as well as prostate specific antigen. PIN is characterized by progressive abnormalities of phenotype which are intermediate between normal prostatic epithelium (NP) and cancer, indicating impairment of cell ...
R, Montironi, A, Santinelli, R, Mazzucchelli   +2 more
openaire   +1 more source

High-Grade Prostatic Intraepithelial Neoplasia in Dogs

European Urology, 1999
The dog is the only nonhuman species in which high-grade intraepithelial neoplasia (HGPIN) and invasive carcinoma spontaneously occur. Our work was the first to describe HGPIN in the dog prostate. Canine HGPIN bears remarkable morphologic similarity to its human counterpart.
openaire   +2 more sources

High grade prostatic intraepithelial neoplasia is a disease

Current Urology Reports, 2001
High grade prostatic intraepithelial neoplasia (PIN) is now widely accepted as the main premalignant lesion that has the potential to progress to prostate adenocarcinoma. High grade PIN is a standard diagnosis that must be included as part of the reported pathologic evaluation of prostate biopsies.
openaire   +2 more sources

Prostatic intraepithelial neoplasia (PIN): Current concepts

Journal of Cellular Biochemistry, 1992
Prostatic intraepithelial neoplasia (PIN) represents the putative precancerous end of the morphologic continuum of cellular proliferations within prostatic ducts, ductules and acini. Two grades of PIN are identified (low grade and high grade), and high grade PIN is considered to be a precursor to invasive carcinoma.
openaire   +2 more sources

Prostatic Intraepithelial Neoplasia

Pathology - Research and Practice, 1995
R. Montironi, P.H. Bartels, D. Thompson, H.G. Bartels, M. Scarpelli   +4 more
openaire   +1 more source

Mimickers of Prostatic Intraepithelial Neoplasia

International Journal of Surgical Pathology, 2010
openaire   +2 more sources

Prostatic intraepithelial neoplasia: an overview.

Reviews in urology, 2011
Prostatic intraepithelial neoplasia (PIN) is the most established precursor of prostatic carcinoma. The presence of prominent nucleoli within an existing duct structure is an easy way to identify the disorder. Four main patterns of high-grade PIN (HGPIN) have been described: tufting, micropapillary, cribriform, and flat.
openaire   +1 more source

Prostatic Intraepithelial Neoplasia

Advances in Anatomic Pathology, 1994
openaire   +1 more source