Results 201 to 210 of about 15,890 (255)
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Cytological features of prostatic intraepithelial neoplasia
Diagnostic Cytopathology, 2006AbstractFine‐needle aspiration cytolotogy (FNAC) is an acknowledged method for diagnosing prostate cancer. False‐positive results are uncommon, but concerns have been raised that prostatic intraepithelial neoplasia (PIN) could be misinterpreted as carcinoma. Therefore, we attempted to describe cytological features of PIN.
Alexander, Valdman +3 more
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Expression of ezrin in prostatic intraepithelial neoplasia
Urology, 2004To study the protein expression and gene copy number of ezrin in a set of high-grade prostatic intraepithelial neoplasia (HGPIN) samples with concomitant prostate cancer. Ezrin is a cytoskeleton linker protein that is actively involved in regulating the growth and metastatic capacity of cancer cells.Nineteen HGPIN samples obtained from radical ...
See-Tong, Pang +6 more
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Molecular biology of prostatic intraepithelial neoplasia
The Prostate, 1996High-grade PIN is the most likely precursor of prostatic adenocarcinoma, according to virtually all available evidence to date. The clinical importance of recognizing PIN is based on its strong association with prostatic carcinoma. PIN has a high predictive value as a marker for adenocarcinoma.
D G, Bostwick +2 more
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Prostatic Intraepithelial Neoplasia and Endocrine Manipulation
European Urology, 1999Prostatic intraepithelial neoplasia (PIN) is the most common precursor lesion of prostatic adenocarcinoma. In 50- to 70-year-old participants of a randomized screening program for prostate cancer (Rotterdam section of the ERSPC) the frequency of high-grade PIN as an isolated finding in sextant prostatic needle biopsies was estimated to be about 1%.
T H, van der Kwast, F, Labrie, B, Têtu
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Follow-Up of Prostatic Intraepithelial Neoplasia
European Urology, 1996Biopsy or fine-needle aspiration cytology are the only appropriate methods for detection of prostatic intraepithelial neoplasia (PIN). PIN has been suggested to be a principal precursor of invasive carcinoma of the prostate. Most reports on an association of PIN and invasive prostatic cancer have a follow-up of less than 1 year, indicating that the ...
A, Berner, F J, Skjørten, S D, Fossà
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Prostatic Intraepithelial Neoplasia
2009Two lesions have been regarded as putative prostatic cancer precursors-prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia (adenosis). PIN is confined within the epithelium without evidence of stromal invasion, although the basal cell layer may be discontinous and focally absent in high-grade PIN.
Guofeng Wang, Maode Lai, Guoping Ren
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Biomarker Expression in Prostatic Intraepithelial Neoplasia
European Urology, 1996This study was conducted to gain a better understanding of the underlying cellular events involved in the development of prostatic intraepithelial neoplasia (PIN) and to clarify the relationship of PIN to invasive prostatic adenocarcinoma (PCa).This article reviews previous studies from our laboratory and others of biomarker expression in PIN and PCa ...
R B, Myers, W E, Grizzle
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Prostatic intraepithelial neoplasia: A premalignant lesion
Journal of Cellular Biochemistry, 1992Putative premalignant changes in the prostate have been recognized for a number of years. A variety of synonyms have been given to the most commonly described lesion, characterized by proliferation and dysplasia of the normal two cell layers lining prostatic acini and ductules; prostatic intraepithelial neoplasia (PIN) is the term most often used.
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[Intraepithelial prostatic neoplasia].
Urologiia i nefrologiia, 200144 patients seeked medical advice for low urinary symptoms. Their examination consisted of digital rectal investigation, test for prostate-specific antigen (PSA) in the serum, transurethral ultrasonic investigation, fine needle multifocal biopsy of the prostate. Three groups were identified by the PSA levels. 7 patients of group 1 had PSA up to 6 ng/ml.
V N, Stepanov, G A, Frank, R R, Dzhioev
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Prostatic intraepithelial neoplasia in dogs with spontaneous prostate cancer
The Prostate, 1997Prostatic intraepithelial neoplasia (PIN) is the most likely precursor of human prostate cancer. The prevalence and immunophenotype of PIN in dogs with spontaneous prostate cancer has not been previously described. To investigate the association between PIN and prostate cancer, we evaluated the prostates of dogs with spontaneous prostate carcinoma. The
D J, Waters +5 more
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