Results 61 to 70 of about 15,814 (254)

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. [PDF]

, 2019
Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations
Aldahl, Joseph, Cardiff, Robert D, Geradts, Joseph, He, Yongfeng, Hooker, Erika, Johnson, Daniel T, Kim, Won Kyung, Le, Vien, Lee, Dong-Hoon, Sun, Zijie, Wu, Huiqing, Yang, Julie S, Yoon, Junhee, You, Sungyong, Yu, Eun-Jeong   +14 more
core  

The Australian Penile Cancer Clinical Registry: a comprehensive national approach to data collection

BJU International, EarlyView.
Background Penile cancer is a rare malignancy, with an Australian incidence of 0.6 in 100 000 men, with a wide range of clinical presentations, from localised, curable tumours to aggressive forms with high morbidity and mortality. Epidemiological data and management guidelines for penile cancer in Australia are limited.
Henry Y.C. Pan, David Homewood, Harrison Lucas, Brendan Dittmer, Jiasian Teh, Jonathan S. O'Brien, Jianliang Liu, Ben Tran, Justin Chee, James A. Churchill, Nathan Lawrentschuk, Niall M. Corcoran   +11 more
wiley   +1 more source

CBP loss cooperates with PTEN haploinsufficiency to drive prostate cancer: implications for epigenetic therapy [PDF]

, 2014
Despite the high incidence and mortality of prostate cancer, the etiology of this disease is not fully understood. In this study, we develop functional evidence for CBP and PTEN interaction in prostate cancer based on findings of their correlate ...
Chen, Shuai, Cheng, Liang, Cheville, John C., Ding, Liya, Huang, Haojie, Liu, Ping, Pan, Yunqian, Regan, Kevin M., Rizzardi, Tony, Schmechel, Stephen C., Tindall, Donald J., van Deursen, Jan, Wang, Liguo, Yu, Chunrong, Zhang, Jun, Zhong, Jian   +15 more
core   +1 more source

The PRAGMATIC pathway ‐ PRostate cancer diAGnosis and MAnagement Triage In Clinical care

BJU International, EarlyView.
Objectives To investigate whether nurse navigator‐led triaging of high‐risk patients may reduce prostate cancer (PCa) diagnosis and treatment times using an in‐house bespoke PRostate cancer diAGnosis and MAnagement Triage In the Clinial care pathway (PRAGMATIC) triaging system, as locally advanced/metastatic disease should be diagnosed and treated ...
Abhishek Sharma, Teresa Campbell, Sagar Kanabar, Hannah Soanes, Ganesh Sathanapally, Anthony Bates, Rincy John, Charlotte Adams, Aisling Brassill, Bryony Lennon, Sanjay Sinha, Louise Flaxman, Vanessa von Hasseln, Philip Camilleri, Ami Sabharwal, Philip Charlton, Gerard Andrade, Mark Tuthill, Andrew Protheroe, Alastair D. Lamb, Tom Leslie, Aaron Leiblich, Francisco Lopez, Clare Verrill, Fergus Gleeson, Ruth MacPherson, Freddie C. Hamdy, Richard Bell, Richard J. Bryant   +28 more
wiley   +1 more source

The implication of initial 24-core transrectal prostate biopsy protocol on the detection of significant prostate cancer and high grade prostatic intraepithelial neoplasia

International Brazilian Journal of Urology, 2011
PURPOSE: To assess the diagnostic value of an initial 24-sample transrectal ultrasound guided (TRUS) prostate biopsy protocol compared to the 10-core technique.
Michael Nomikos, Ioannis Karyotis, Prodromos Phillipou, Charalambos Constadinides, Dimitrios Delakas   +4 more
doaj   +1 more source

The value of immunohistochemical research on PCNA, p53 and heat shock proteins in prostate cancer management: a review. [PDF]

, 2006
This review addresses the significance of the expression of proliferating cell nuclear antigen (PCNA), p53 and some heat shock proteins (Hsps) in prostate carcinoma (PC).
ANZALONE, Rita, BUCCHIERI, Fabio, CAMPANELLA, Claudia, CAPPELLO, Francesco, CZARNECKA, AM, PALMA, Antonio, RIBBENE, Anna, ZUMMO, Giovanni   +7 more
core  

Clinicopathologic features of incidental prostatic adenocarcinoma in radical cystoprostatectomy specimens [PDF]

, 2011
Background The aim of this study is to review all features of incidentally discovered prostate adenocarcinoma in patients undergoing radical cystoprostatectomy for bladder cancer.
Berna Aytac, Hakan Vuruskan
core   +1 more source

Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner

BJU International, EarlyView.
Objectives To evaluate the feasibility and diagnostic performance of ex vivo fluorescence confocal microscopy (FCM) using the Histolog® Scanner (SamanTree Medical SA, Lausanne, Switzerland) for the assessment of penile cancer (PeCa) specimens, and to compare FCM‐based diagnoses with standard formalin‐fixed, paraffin‐embedded (FFPE) histopathology ...
Xiaohu Zhang, Ricardo Almeida‐Magana, Larissa Sena Teixeira Mendes, Daniela Fleck Lavergne, Hussain Alnajjar, Greg Shaw, Alex Freeman, Asif Muneer, Aiman Haider   +8 more
wiley   +1 more source

A Combination of Xanthohumol and Ursolic Acid in the Diet Leads to Synergistic Inhibition of Prostate Cancer Progression

Molecular Carcinogenesis, Volume 65, Issue 4, Page 508-522, April 2026.
ABSTRACT Prostate cancer (PCa) is the second most common cancer and second leading cause of cancer death for American men. Chemoprevention by using phytochemicals offers a promising approach to improve outcomes due to their ability to act on cancer cell metabolism and growth while maintaining low toxicity profiles.
Rachel Clark, Achinto Saha, G. Lavender Hackman, Chelsea A. Friedman, Ruggiero Gorgoglione, Stefano Tiziani, John DiGiovanni   +6 more
wiley   +1 more source

Small cell-like change in prostatic adenocarcinoma and intraductallesions – neuroendocrine or not?

Surgical and Experimental Pathology, 2022
Background Small cell-like change in prostatic neoplasia (both invasive adenocarcinoma and intraepithelial lesions) is described in three previous reports. None of them to date proved to be associated with overt prostate neuroendocrine carcinoma.
Daniel Abensur Athanazio, Maiara Ferreira de Souza   +1 more
doaj   +1 more source