Results 81 to 90 of about 80,911 (249)
Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins
Scientific Reports, 2017 Mamba venoms contain a multiplicity of three-finger fold aminergic toxins known to interact with various α-adrenergic, muscarinic and dopaminergic receptors with different pharmacological profiles.
Guillaume Blanchet +8 more
doaj +1 more source
Research on animal nutrition at ITC [PDF]
, 2003 La mission était centrée sur les aspects Nutrition à l'ITC de Banjul (Gambie). Elle a débuté par un atelier portant sur l'état de la recherche en nutrition en Afrique de l'Ouest. L'atelier rassemblait des représentants ITC, ISRA (Senegal), CIRDES et ILRI
Lecomte, Philippe
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Domestication et fonction nutrition chez les poissons
INRAE Productions Animales, 2004 L’objectif de cet article est d’évaluer dans quelle mesure l’étude du régime alimentaire des poissons peut indiquer les possibilités et les contraintes liées à leur domestication.
C. CAHU
doaj +1 more source
Influence des protéines et des lipides chez le diabétique de type 1: un outil pour la pratique : travail de Bachelor [PDF]
, 2016 Introduction : Actuellement, la méthode du calcul des hydrates de carbone pratiquée à travers l’insulinothérapie est la méthode de référence dans la prise en charge du diabète de type 1 (DT1) pour déterminer la dose d’insuline prandiale.
Aebi, Anouk +2 more
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Toxins, 2019 Over the two last decades, venom toxins have been explored as alternatives to opioids to treat chronic debilitating pain. At present, approximately 20 potential analgesic toxins, mainly from spider venoms, are known to inhibit with high affinity the NaV1.
Tânia C. Gonçalves +9 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Utilisation alimentaire des dérivés des cotonniers sans gossypol [PDF]
, 1987 Le procédé industriel classique d'extraction de l'huile est rappelé. Une technologie améliorée d'extraction directe par solvant permet d'obtenir une farine utilisable en alimentation humaine.
Marquié, Catherine
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