Potential role of bcl-2 as a suppressor of tumour angiogenesis in non- small-cell lung cancer
It has been reported that genes regulating apoptosis may play a role in tumoral angiogenesis. This study examined the relationship between tumour vascularization, a measure of tumour angiogenesis, and bcl-2 and p53 expression in operable non-small-cell ...
Giatromanolaki, A. +6 more
core +1 more source
Bcl-2 can suppress apoptosis by controlling genes that encode proteins required for programmed cell death and by interference with peroxidative damage.
侯自銓;林仁混 +1 more
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Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation [PDF]
Two interleukin-2 receptor-dependent signaling pathways have thus far been identified: the c-fos/c-jun induction pathway mediated by src family protein-tyrosine kinases and the c-myc induction pathway.
Liu, Zhao-Jun +8 more
core +1 more source
Alphaviruses induce apoptosis in Bcl-2-overexpressing cells: evidence for a caspase-mediated, proteolytic inactivation of Bcl-2 [PDF]
Bcl-2 oncogene expression plays a role in the establishment of persistent viral infection by blocking virus-induced apoptosis. This might be achieved by preventing virus-induced activation of caspase-3, an IL-1beta-converting enzyme (ICE)-like cysteine ...
Grandgirard, Denis +6 more
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Detecção imunoistoquímica de fatores relacionados à proliferação celular e ao mecanismo da apoptose em cistos radiculares e dentígeros [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2009.Esse estudo propôs investigar os aspectos relacionados à proliferação celular e ao mecanismo da ...
Martins, Caroline Alberici
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B-cell leukemia/lymphoma (bcl-2) expression can override the apoptosis development in lymphoid and hormonally regulated tissue-like breast. The presence of estrogen receptor (ER), progesterone receptor (PR), and androgen receptor (AR) have revealed in ...
H J Wolfe (100282) +3 more
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Bad expression influences time to androgen escape in prostate cancer [PDF]
<b>OBJECTIVE</b>: To assess the role of selected downstream Bcl-2 family members (Bad, Bax, Bcl-2 and Bcl-xL) in the development of androgen-independent prostate cancer (AIPC), as androgen-deprivation therapy is the treatment of choice in ...
Teo, K. +4 more
core +1 more source
Avaliação da funcionalidade e do efeito da lipofilização em proteínas de farinha totalmente desengordurada de amendoim (Archis hypogaea Lineau) [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Agrárias. Programa de Pós-Graduação em Ciência dos Alimentos.Foram lipofilizadas proteínas de farinha desengordurada de amendoim com Cloreto de ácido palmítico, em três ...
Ferreyra, Julieta Clarisa
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Yeast as a tool for studying proteins of the Bcl-2 family
Permeabilization of the outer mitochondrial membrane that leads to the release of cytochrome c and several other apoptogenic proteins from mitochondria into cytosol represents a commitment point of apoptotic pathway in mammalian cells. This crucial event
Petra Jaká, Marek Mentel, Peter Polčic
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Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
Approximately half of the neurons produced during embryogenesis normally die before adulthood. Although target-derived neurotrophic factors are known to be major determinants of programmed cell death--apoptosis--the molecular mechanisms by which trophic ...
Martinou, J. C. +3 more
core +1 more source

