Results 31 to 40 of about 6,469,838 (241)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Termodinàmica de gels. Gels de Pectina [PDF]
, 2013 Títol del póster : Thermodynamics of gels : pectin ...
Llagostera, Emilio +1 more
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Perfils nutricionals de la carn i dels productes fets a base de carn [PDF]
, 2010 L'article presentamolt breument les diverses categories de productes carnis amb vuit taules de dades indicatives de composició i dades de productes elaborats a base de carn.The article presents briefly the various categories of meat products with eight
Bauer, Friedrich, Honikel, Karl-Otto
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The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Test per estudiar proteïnes implicades en malalties neurodegeneratives [PDF]
, 2011 Investigadors de l'Institut de Biotecnologia i Biomedicina i del Departament de Bioquímica i Biologia Molecular han desenvolupat i patentat un mètode amb el llevat Saccharomyces cerevisiae per detectar en proteïnes humanes la formació de petits grups ...
Ventura, Salvador
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Microestructura i propietats dels aliments [PDF]
, 2005 La microestructura dels aliments està directament afectada pels canvis químics i bioquímics soferts a través del seu processament, i d'aquesta depenen, majoritàriament, les propietats finals, buscades o indesitjables, de l'aliment elaborat.
Lluch, M. Àngels
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Desxifrant la base molecular de la formació de l'ou en els peixos marins [PDF]
, 2009 La hidratació de l'oòcit de peixos marins durant les darreres fases de la formació de l'ou és un factor crític per al desenvolupament i supervivència correctes de l'embrió.
Cerdà Luque, Joan
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