Results 251 to 260 of about 3,932,956 (396)

Molecular Modeling of Anti HIV Drugs of Protease Inhibitor Group by CoMFA

, 2019
M B Kalhans, A. K. Singh, Nidhi Singh
openalex   +1 more source

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Regioselective multicomponent synthesis of α-boryl ureas: discovery of a potent main protease inhibitor.

Org Biomol Chem
Gyasi YI, Nyalata S, Pa S, Gunasekera D, Vulupala VR, Mallampudi NR, Ramidi GR, Xu S.   +7 more
europepmc   +1 more source

Secretory leucocyte protease inhibitor regulates bone metabolism and inflammation in experimental mouse periodontitis. [PDF]

Commun Biol
Sasagawa K, Domon H, Hirayama S, Maekawa T, Isono T, Tabeta K, Terao Y.   +6 more
europepmc   +1 more source

L-696,474, a novel cytochalasin as an inhibitor of HIV-1 protease. II. Isolation and structure.

, 1992
John G. Ondeyka, Otto D. Hensens, Deborah L. Zink, Richard Ball, R. B. Lingham, Gerald F. Bills, Anne W. Dombrowski, Michael Goetz   +7 more
openalex   +2 more sources

Improving the efficacy of proteasome inhibitors in the treatment of renal cell carcinoma by combination with the human immunodeficiency virus ( HIV )‐protease inhibitors lopinavir or nelfinavir [PDF]

, 2017
Dominik Abt, Andrej Bešše, Lenka Sedlaříková, Marianne Kraus, Juergen Bader, Tobias Silzle, Martina Vodinská, Ondřej Slabý, Hans‐Peter Schmid, Daniel Engeler, Christoph Driessen, Lenka Bešše   +11 more
openalex   +1 more source

The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor

Proceedings of the National Academy of Sciences of the United States of America, 2003
Haitao Yang, Maojun Yang, Yi Ding, Yiwei Liu, Z. Lou, Zhe Zhou, Lei Sun, L. Mo, S. Ye, H. Pang, G. Gao, K. Anand, M. Bartlam, R. Hilgenfeld, Z. Rao   +14 more
semanticscholar   +1 more source

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

Secretory leukocyte protease inhibitor influences periarticular joint inflammation in <i>Borrelia burgdorferi</i>-infected mice. [PDF]

Elife
Yu Q, Tang X, Hart T, Homer R, Belperron AA, Bockenstedt LK, Ring A, Nakamura A, Fikrig E.   +8 more
europepmc   +1 more source

Detection of protease and protease inhibitors during development of soybean crown nodules

, 2010
L.A. Mashamba
openalex   +1 more source