Results 231 to 240 of about 793,529 (384)

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Development of Efficient Expression Systems for Bacteriolytic Proteases L1 and L5 of <i>Lysobacter capsici</i> XL1. [PDF]

Int J Mol Sci
Kudryakova I, Afoshin A, Leontyevskaya E, Leontyevskaya N.   +3 more
europepmc   +1 more source

Effects of Drying Condition of Vitamin A Contents and Protease of the Liver of Whale

, 1941
Yosimiti MIYAMA, Kuman SARUYA, Yasuhiro SAKAKI, Masayuki Asakura   +3 more
openalex   +2 more sources

Studies on the mode of action of excess of vitamin A. 3. Release of a bound protease by the action of vitamin A [PDF]

, 1961
J. T. Dingle
openalex   +1 more source

Unleashing the therapeutic potential of human kallikrein-related serine proteases

Nature reviews. Drug discovery, 2015
I. Prassas, Azza Eissa, G. Poda, E. Diamandis   +3 more
semanticscholar   +1 more source

Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery

Advanced Functional Materials, EarlyView.
This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer, Min Jiang, Adrian Kromer, Anny Nguyen, Müge Molbay, Simone Pinto Carneiro, David Jürgens, Gerald Burgstaller, Bastian Popper, Benjamin Winkeljann, Olivia Monika Merkel   +10 more
wiley   +1 more source

The secreted proteases <i>aur, scpA, sspA and sspB</i> suppress the virulence of <i>Staphylococcus aureus</i> USA300 by shaping the extracellular proteome. [PDF]

Virulence
Li X, Maaß S, Ferrero-Bordera B, Zhang Z, Wang M, Sietsema E, Liu L, Divinagracia M, van Dijl JM, Buist G.   +9 more
europepmc   +1 more source

Studies on Tissue Protease

, 1955
Fumio Honma Ito
openalex   +2 more sources

Transmembrane Activation of Catalysis and Protein Refolding in Synthetic Cells by Enzymes and Nanozymes

Advanced Functional Materials, EarlyView.
Synthetic cells are engineered herein to respond to an external chemical messenger by the activation of intracellular catalysis. The chemical messenger molecules are catalytically generated by an extracellular enzyme or a mineral surface, whereas the intracellular catalysis emerges via direct enzyme activation or via protein refolding.
Dante G. Andersen, Andreas B. Pedersen, Mireia Casanovas Montasell, Søren Moesgaard, Anja Bille Bohn, Alexander N. Zelikin   +5 more
wiley   +1 more source

Schistosoma japonicum cathepsin L1: A potential target for anti-schistosomiasis strategies. [PDF]

PLoS Negl Trop Dis
Piao X, Wang Y, Jiang N, Cai P, Duan J, Liu S, Chen Q, Hou N.   +7 more
europepmc   +1 more source