Results 31 to 40 of about 333,858 (311)

Protein Quality Control at the Sarcomere: Titin Protection and Turnover and Implications for Disease Development

open access: yesFrontiers in Physiology, 2022
Sarcomeres are mainly composed of filament and signaling proteins and are the smallest molecular units of muscle contraction and relaxation. The sarcomere protein titin serves as a molecular spring whose stiffness mediates myofilament extensibility in ...
Sebastian Kötter, Martina Krüger
doaj   +1 more source

CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets

open access: yesMatrix Biology Plus, 2019
Macrophage plasticity, cellular origin, and phenotypic heterogeneity are perpetual challenges for studies addressing the biology of this pivotal immune cell in development, homeostasis, and tissue remodeling/repair.
Henrik J. Jürgensen   +7 more
doaj   +1 more source

Purification and characterization of a protease from Aspergillus sydowii URM5774: Coffee ground residue for protease production by solid state fermentation

open access: yesAnais da Academia Brasileira de Ciências, 2021
Solid state fermentation is a promising technology largely used in biotechnology process and is a suitable strategy for producing low-cost enzymatic products.
FELYPE T.B. ROCHA   +6 more
doaj   +1 more source

A comprehensive nomenclature for serine proteases with homology to tissue kallikreins [PDF]

open access: yes, 2006
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins
Scorilas, Andreas   +61 more
core   +1 more source

Purification and characterization of novel fibrinolytic proteases as potential antithrombotic agents from earthworm Perionyx excavatus [PDF]

open access: yes, 2011
Six protease fractions, namely FI, FII, FIII-1, FIII-2, FIII-3 and FIV, were isolated from Perionyx excavatus earthworm biomass by acetone precipitation, followed by serial chromatography using anion exchange, hydrophobic interaction and size exclusion ...
Giang Duong   +12 more
core   +1 more source

Reduce, Reuse and Recycle in Protein Chromatography: Development of an Affinity Adsorbent from Waste Paper and Its Application for the Purification of Proteases from Fish By-Products

open access: yesBiomolecules, 2020
In the present study, we report the development of a cellulose-based affinity adsorbent and its application for the purification of proteases from fish by-products.
Georgios E. Premetis, Nikolaos E. Labrou
doaj   +1 more source

Independent Subtilases Expansions in Fungi Associated with Animals [PDF]

open access: yes, 2011
Many socially important fungi encode an elevated number of subtilisin-like serine proteases, which have been shown to be involved in fungal mutualisms with grasses and in parasitism of insects, nematodes, plants, other fungi, and mammalian skin.
P. Szczesny   +7 more
core   +2 more sources

Microbial proteases and their applications [PDF]

open access: yes, 2023
Proteases (proteinases or peptidases) are a class of hydrolases that cleave peptide chains in proteins. Endopeptidases are a type of protease that hydrolyze the internal peptide bonds of proteins, forming shorter peptides; exopeptidases hydrolyze the ...
Xue Zhang   +6 more
core   +1 more source

Biological and Enzymatic Characterization of Proteases from Crude Venom of the Ant Odontomachus bauri

open access: yesToxins, 2015
Hymenoptera venoms constitute an interesting source of natural toxins that may lead to the development of novel therapeutic agents. The present study investigated the enzymatic and biological characteristics of the crude venom of the ant Odontomachus ...
Mariana Ferreira Silva   +9 more
doaj   +1 more source

Interplay between the Hsp90 Chaperone and the HslVU Protease To Regulate the Level of an Essential Protein in Shewanella oneidensis

open access: yesmBio, 2019
Protein synthesis, folding, and degradation are an accurately regulated process occurring in every organism and called proteostasis. This process is essential to maintain a healthy proteome since proteostasis dysregulation is responsible for devastating ...
Flora Ambre Honoré   +3 more
doaj   +1 more source

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