Clostridium butyricum MIYAIRI 588-Induced Protectin D1 Has an Anti-inflammatory Effect on Antibiotic-Induced Intestinal Disorder [PDF]
Frontiers in Microbiology, 2020 Metabolites are thought as the end products in cellular regulatory processes and their levels show the strongest relationships with the phenotype. Previously, we showed that the administration of Clostridium butyricum MIYAIRI 588 (CBM 588) upregulated ...
Kenta Iwasaki +2 more
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The specialized pro-resolving lipid mediator Protectin D1 affects macrophages differentiation and activity in Adult-onset Still’s disease and COVID-19, two hyperinflammatory diseases sharing similar transcriptomic profiles [PDF]
Frontiers in Immunology, 2023 IntroductionCOVID-19 and autoinflammatory diseases, such as Adult-onset Still’s Disease (AOSD), are characterized by hyperinflammation, in which it is observed massive production and uncontrolled secretion of pro-inflammatory cytokines.
Francesco Ursini +2 more
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Protectin D1 ameliorates non-compressive lumbar disc herniation through SIRT1-mediated CGRP signaling [PDF]
Molecular PainBackground . Neuro-inflammatory response promotes the initiation and sustenance of lumbar disc herniation (LDH). Protectin D1 (PD1), as a new type of specialized pro-resolving mediator (SPM), can improve the prognosis of various inflammatory diseases ...
Yu-Chang Zhu +5 more
doaj +2 more sources
Circulating Protectin D1 and Neutrophils Extracellular Traps in the Diagnosis and Progression of Acute Pancreatitis [PDF]
Journal of Inflammation ResearchZhiyang Wu,1,* Wenjun Lu,2,* Xin Zhang,1 Qiaoying Xia,2 Han Zuo,2 Xi Guo,1 Yu Liu,1 Fan Zhang,3 Xin Zhang,4 Luyao Zhang2 1Department of Critical Care Medicine, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao ...
Wu Z +9 more
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Protectin DX resolves fracture-induced postoperative pain in mice via neuronal signaling and GPR37-activated macrophage efferocytosis [PDF]
The Journal of Clinical InvestigationProtectin DX (PDX) is a member of the superfamily of specialized proresolving mediators and exerts anti-inflammatory actions in animal models; however, its signaling mechanism remains unclear.
Yize Li +7 more
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Bioactive lipid mediator class switching regulates myogenic cell progression and muscle regeneration [PDF]
Nature CommunicationsThe muscle stem cell niche is well-described as influencing myogenic cell fate decision; however, the intrinsic mechanisms driving muscle stem cell progression during myogenesis are not yet fully elucidated.
Paul Fabre +11 more
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Stereocontrolled total synthesis of Neuroprotectin D1/Protectin D1 and its aspirin-triggered stereoisomer [PDF]
Tetrahedron Letters, 2012 Nicos Petasis +2 more
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Biomedicines, 2021 The gut microbiome is closely related to gut metabolic functions, and the gut microbiome and host metabolic functions affect each other. Clostridium butyricum MIYAIRI 588 (CBM 588) upregulates protectin D1 production in host colon tissue following G ...
Tadashi Ariyoshi +9 more
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Frontiers in Immunology, 2021 Viral pneumonias are a major cause of morbidity and mortality, owing in part to dysregulated excessive lung inflammation, and therapies to modulate host responses to viral lung injury are urgently needed.
Katherine H. Walker +5 more
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Innate immunity is a key factor for the resolution of inflammation in asthma [PDF]
European Respiratory Review, 2015 The resolution of inflammation is an integral and natural part of the physiological response to tissue injury, infection and allergens or other noxious stimuli.
Cindy Barnig, Bruce D. Levy
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