Results 71 to 80 of about 188,216 (142)

ELISPOT assay to measure antigen-specific murine CD8(+) T cell responses.

, 2001
The enzyme-linked immunospot technique (ELISPOT) relies on the visualization of cytokine secretion by individual T cells following in vitro stimulation with antigen. This assay has been developed and standardized for the quantitative detection of antigen-
Carvalho, LH, Hafalla, JC, Zavala, F
core   +1 more source

Influenza and memory T cells : how to awake the force [PDF]

, 2016
Annual influenza vaccination is an effective way to prevent human influenza. Current vaccines are mainly focused on eliciting a strain-matched humoral immune response, requiring yearly updates, and do not provide protection for all vaccinated individuals.
Glezen, Hartshorn, Hufford, Jin, Jordan, Luo, Mosmann, Razvi, Topham, Topham, Topham, Von Andrian, Wijburg   +12 more
core   +3 more sources

Bacillus anthracis edema factor substrate specificity: evidence for new modes of action [PDF]

, 2012
Since the isolation of Bacillus anthracis exotoxins in the 1960s, the detrimental activity of edema factor (EF) was considered as adenylyl cyclase activity only.
Agrawal, Altaweel, Basler, Bauche, Bell, Benson, Beste, Bock, Bond, Boyd, Bradley, Brown, Burhenne, Carbonetti, Carbonetti, Carson-Walter, Casteel, Christensen, Christensen, Confer, Copsel, Crawford, Crowe, Cunningham, Dalkas, Defer, Deuquet, Ding, Drum, Duesbery, Feld, Firoved, Friedlander, Fu, Fukuhara, Gaion, Gille, Gordon, Göttle, Hammerschmidt, He, Helfman, Hong, Ivarsson, Jernigan, Johnson, Katayama, Katayama, Kaupp, Kintzer, Klimpel, Laine, Larabee, Larabee, Leppla, Liu, Martin Göttle, McDonough, Milne, Mogridge, Mogridge, Newton, Newton, Newton, Newton, Newton, Oncu, O´Brien, Park, Petosa, Pezard, Postea, Puhar, Roland Seifert, Santelli, Scobie, Scobie, Scorpio, Shapiro, Shen, Shirshev, Soelaiman, Stefan Dove, Sun, Tamayo, Taylor, Taylor, Tesmer, Thomas, Tournier, Vitale, Vitale, Vojtova, Yeager, Zong   +94 more
core   +2 more sources

Anthrax Vaccines in the 21st Century

Vaccines
Vaccination against Bacillus anthracis is the best preventive measure against the development of deadly anthrax disease in the event of exposure to anthrax either as a bioweapon or in its naturally occurring form.
Apostolos P. Georgopoulos, Lisa M. James
doaj   +1 more source

Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response. [PDF]

, 2019
Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable responses ...
Fong, Lawrence, Keenan, Bridget P, Kelley, Robin K   +2 more
core   +2 more sources

REGULATORY ROLE OF OX22HIGH T-CELLS IN MERCURY-INDUCED AUTOIMMUNITY IN THE BROWN NORWAY RAT [PDF]

, 1993
The monoclonal antibody OX22 defines a functional split within CD4+ T cells in the rat, with OX22high cells mainly producing interleukin 2 (IL-2) and interferon γ and responsible for delayed-type hypersensitivity responses, and OX22low cells mainly ...
Mathieson, PW, Oliveira, DB, Thiru, S
core   +1 more source

Biochip for the Detection of Bacillus anthracis Lethal Factor and Therapeutic Agents against Anthrax Toxins

Membranes, 2016
Tethered lipid bilayer membranes (tBLMs) have been used in many applications, including biosensing and membrane protein structure studies. This report describes a biosensor for anthrax toxins that was fabricated through the self-assembly of a tBLM with B.
Vitalii Silin, John J. Kasianowicz, Ariel Michelman-Ribeiro, Rekha G. Panchal, Sina Bavari, Joseph W. F. Robertson   +5 more
doaj   +1 more source

The host immune response to gastrointestinal nematode infection in sheep [PDF]

, 2015
non peer reviewedGastrointestinal nematode infection represents a major threat to the health, welfare and productivity of sheep populations worldwide. Infected lambs have a reduced ability to absorb nutrients from the gastrointestinal tract, resulting in
Abraham, Ahmed, Akiho, Amarante, Andronicos, Anthony, Balic, Balic, Balic, Balic, Becattini, Beraldi, Bishop, Bisset, Bisset, Bowdridge, Brunsdon, Brunsdon, Brunsdon, Buddle, Cardia, Clarke, Conway, Coop, Craig, Craig, Crespo, Dawicki, Deplancke, deSchoolmeester, Diez-Tascon, Donaldson, Douch, Douch, Dunsmore, Else, Finkelman, Finkelman, Finney, French, Fuhrman, Geijtenbeek, Gilfillan, Gill, Glass, Gossner, Gossner, Grainger, Halliday, Hansen, Harriman, Harrison, Harrison, Hassan, Hassan, Henderson, Hogan, Houdijk, Hsieh, Huntley, Huntley, Huntley, Ingham, Khan, Kim, Kooyman, Korn, Lacroux, Lazarevic, Lighvani, MacKinnon, Madden, Malan, Mantovani, Marson, McClure, McGuckin, McKenna, McRae, McSorley, Meeusen, Mori, Nair, Ohkura, Paul, Pernthaner, Pernthaner, Pettit, Rainbird, Rosenberg, Sangster, Scott, Seaton, Shakya, Shaw, Shaw, Smith, Smith, Stear, Stear, Stear, Stear, Stevenson, Stone, Strain, Sutherland, Szabo, Taylor, Terefe, Urb, Vallance, Vignali, Voehringer, Williams   +113 more
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Role of the Antigen Capture Pathway in the Induction of a Neutralizing Antibody Response to Anthrax Protective Antigen

mBio, 2018
Toxin neutralizing antibodies represent the major mode of protective immunity against a number of toxin-mediated bacterial diseases, including anthrax; however, the cellular mechanisms that lead to optimal neutralizing antibody responses remain ill ...
Anita Verma, Miriam M. Ngundi, Gregory A. Price, Kazuyo Takeda, James Yu, Drusilla L. Burns   +5 more
doaj   +1 more source

Protective Effect of Sera from Animals Treated with Different Brucella Antigens upon Brucella Infection in Mice [PDF]

, 1953
I. Live, L. Giuliani
openalex   +1 more source