FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
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A Narrative Review of Protective Factors that Predict Enculturation Processes for Latinx Individuals in the U.S. [PDF]
, 2020 A Narrative Review of Protective Factors that Predict Enculturation Processes for Latinx Individuals in the U.S. Jane Sun, Dept. of Psychology, Jennifer Rodriguez, Alanna Cason, Yessica Flores, Karl Villareal, Arlenis Santana, Dept.
Cason, Alanna +6 more
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Methods and approaches to improving the emotional health and well being of children: A briefing paper concerning interventions to prevent internalising disorders [PDF]
, 2008 This paper presents a summary of the prevalence of somatic, anxiety and depressive disorders in children and of the known risk and protective factors associated with these problems.
Smith, Marjorie, Storey, Pamela
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Childhood Psychosocial Determinants of Cardiovascular Health [PDF]
, 2016 Understanding risk and protective factors that impact cardiovascular health is of utmost importance. There is ample evidence that cardiovascular health begins in childhood, tracks over time, and is subject to adverse social influences. This paper reviews
Gidding, Samuel S., Sood, Erica D.
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Cyberbullying: Definition, Prevalence, Effects, Risk and Protective Factors
Psikiyatride Güncel YaklaşımlarCyberbullying is defined as intentional, repetitive, and harmful behaviors carried out using computers, cell phones, or other electronic devices. In recent years, there has been an increase in the rates of cyberbullying parallel to the rise in Internet ...
Burak Akdeniz, Aysun Doğan
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Clinical and Genetic Risk Factors Associated with Psoriatic Arthritis among Patients with Psoriasis. [PDF]
, 2018 IntroductionPsoriatic arthritis (PsA) is a chronic, inflammatory arthritis that affects an estimated 30% of patients with psoriasis. PsA is underdiagnosed in primary care and dermatology clinics due to a variety of reasons, including failure of ...
Ahn, Richard +3 more
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The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Intervention strategies for children and adolescent with disorders: from intrapsychic to transactional perspective [PDF]
, 2015 A large amount of studies and clinical evidence document the importance of infancy and early childhood influences on long term developmental trajectories toward mental health or psychopathology (Sameroff, 2000, 2010).
LANGHER, Viviana, S. Cataudella
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