Results 81 to 90 of about 17,058,241 (360)

Risk and protective factors for child development: An observational South African birth cohort

PLoS Medicine, 2019
Background Approximately 250 million (43%) children under the age of 5 years in low- and middle-income countries (LMICs) are failing to meet their developmental potential.
K. Donald, C. Wedderburn, W. Barnett, Raymond T Nhapi, A. Rehman, J. A. Stadler, N. Hoffman, N. Koen, H. Zar, Dan J Stein   +9 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Influencing factors for residual kidney function in incident peritoneal dialysis patients: a systematic review and meta-analysis

Renal Failure, 2023
Background Residual kidney function (RKF) impacts patients’ survival rate and quality of life when undergoing peritoneal dialysis (PD). This meta-analysis was conducted to systematically identify risk and protective factors associated with RKF decline ...
Dan Zhou, Hong Lei, Shuran Wu, Wei Yang, Wenting Cui, Longkai Li, Hongli Lin, Anchun Yin   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Influence of Protective and Risk Factors on Resilience among Family Caregivers of Schizophrenia Patients

Journal of Nursing Practice
Background: Developing resilience among family caregivers of schizophrenia patients is challenging. Families must be able to identify risk factors and manage them to achieve a dynamic family situation and have the ability to survive while caring for ...
Faizatur Rohmi, Dita Kurnia Sari, Arik Agung Setiawan   +2 more
doaj   +1 more source

Multi-Level Protective Factors of Adolescent Smoking and Drinking

European Journal of Investigation in Health, Psychology and Education, 2023
Adolescence is the most critical life stage for experimentation with substance use; however, this is also the most suitable period for strengthening protective factors and thus promoting adult physical and mental health.
Réka Dudok, Bettina F. Piko
doaj   +1 more source

Performing against the odds: developmental trajectories of children in the EPPSE 3-16 study [PDF]

, 2011
This study explores how risks and protective factors shape children's learning and why it leads to academic resilience for some, not ...
Mayo, Aziza, Melhuish, Edward, Sammons, Pam, Siraj-Blatchford, Iram, Sylva, Kathy, Taggart, Brenda   +5 more
core  

Trends and correlates of marijuana use among late middle-aged and older adults in the United States, 2002–2014 [PDF]

, 2017
BACKGROUND: Recent trend studies suggest that marijuana use is on the rise among the general population of adults ages 18 and older in the United States.
AbiNader, Millan, Cummings-Vaughn, Lenise A., Holzer, Katherine J., Nelson, Erik J., Oh, Sehun, Salas-Wright, Christopher P., Vaughn, Michael G.   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Risk and Protective Factors of Psychological Distress in Patients Who Recovered From COVID-19: The Role of Cognitive Reserve

Frontiers in Psychology, 2022
Recent studies reported the development of psychological distress symptoms in patients who recovered from COVID-19. However, evidence is still scarce and new data are needed to define the exact risk and protective factors that can explain the variability
Maria Devita, Elisa Di Rosa, Pamela Iannizzi, Sara Bianconi, Sara Anastasia Contin, Simona Tiriolo, Marta Ghisi, Marta Ghisi, Rossana Schiavo, Nicol Bernardinello, Elisabetta Cocconcelli, Elisabetta Balestro, Anna Maria Cattelan, Davide Leoni, Biancarosa Volpe, Daniela Mapelli   +15 more
doaj   +1 more source