Results 1 to 10 of about 3,348,135 (183)

Unified Alignment of Protein-Protein Interaction Networks [PDF]

Scientific Reports, 2017
Paralleling the increasing availability of protein-protein interaction (PPI) network data, several network alignment methods have been proposed. Network alignments have been used to uncover functionally conserved network parts and to transfer annotations.
Noël Malod-Dognin, Kristina Ban, Nataša Pržulj   +2 more
doaj   +2 more sources

Protein-protein interaction prediction using bidirectional GRUs with explicit ensemble. [PDF]

PLoS One
Lan Q, Zheng Z, Tang Z, Qiu X, Yin Z.
europepmc   +2 more sources

Fast Solution-Phase and Liquid-Phase Peptide Syntheses (SolPSS and LPPS) Mediated by Biomimetic Cyclic Propylphosphonic Anhydride (T3P^®)

Molecules, 2023
The growing applications of peptide-based therapeutics require the development of efficient protocols from the perspective of an industrial scale-up. T3P® (cyclic propylphosphonic anhydride) promotes amidation in the solution-phase through a biomimetic ...
Alexia Mattellone, Dario Corbisiero, Paolo Cantelmi, Giulia Martelli, Chiara Palladino, Alessandra Tolomelli, Walter Cabri, Lucia Ferrazzano   +7 more
doaj   +1 more source

Identification of photocrosslinking peptide ligands by mRNA display

Communications Chemistry, 2023
Photoaffinity labelling is a promising method for studying protein-ligand interactions. However, obtaining a specific, efficient crosslinker can require significant optimisation.
Yuteng Wu, M. Teresa Bertran, Dhira Joshi, Sarah L. Maslen, Catherine Hurd, Louise J. Walport   +5 more
doaj   +1 more source

Comparing human–Salmonella with plant–Salmonella protein–protein interaction predictions [PDF]

Frontiers in Microbiology, 2015
Salmonellosis is the most frequent foodborne disease worldwide and can be transmitted to humans by a variety of routes, especially via animal and plant products. Salmonella bacteria are believed to use not only animal and human but also plant hosts despite their evolutionary distance. This raises the question if Salmonella employs similar mechanisms in
Sylvia eSchleker, Sylvia eSchleker, Meghana eKshirsagar, Judith eKlein-Seetharaman   +3 more
openaire   +4 more sources

Developing methods to study conformational changes in RNA crystals using a photocaged ligand

Frontiers in Molecular Biosciences, 2022
Crystallographic observation of structural changes in real time requires that those changes be uniform both spatially and temporally. A primary challenge with time-resolved ligand-mixing diffraction experiments is asynchrony caused by variable factors ...
Hyun Kyung Lee, Chelsie E. Conrad, Valentin Magidson, William F. Heinz, Gary Pauly, Ping Yu, Saminathan Ramakrishnan, Jason R. Stagno, Yun-Xing Wang   +8 more
doaj   +1 more source

Fitting a geometric graph to a protein-protein interaction network [PDF]

, 2008
Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between network structure and biological function as well as into evolution.
Barabási, Bender, Bradley, Cox, Desmond J. Higham, Erdös, Erdös, Gavin, Giot, Golub, Grindrod, Grindrod, Higham, Ho, Ito, Kaski, Khanin, Krogan, Lappe, Li, Marija Rašajski, Mewes, Milo, Morrison, Mrowka, Nataša Pržulj, Newman, Penrose, Peri, Pržulj, Pržulj, Pržulj, Pržulj, Rual, Simon, Stelzl, Taguchi, Tape, Thomas, Titz, Uetz, Vazquez, von Mering, Watts, Xenarios, Zanzoni, Zhong   +46 more
core   +3 more sources

Increased Pentraxin 3 Levels Correlate With IVIG Responsiveness and Coronary Artery Aneurysm Formation in Kawasaki Disease

Frontiers in Immunology, 2021
Kawasaki disease (KD) is a febrile disease of childhood characterized by systemic vasculitis that can lead to coronary artery lesions (CAL). This was a prospective cohort study to determine the levels of the pentraxin 3 (PTX3), soluble CD24-Subtype ...
Toshiyuki Kitoh, Toshiyuki Kitoh, Tsuyoshi Ohara, Taichiro Muto, Akihisa Okumura, Reizo Baba, Reizo Baba, Yusuke Koizumi, Yuka Yamagishi, Hiroshige Mikamo, Kenji Daigo, Takao Hamakubo   +11 more
doaj   +1 more source

Visualizing RNA conformational and architectural heterogeneity in solution

Nature Communications, 2023
RNA conformational heterogeneity is important to diverse functions. Here, the authors use AFM to directly visualize individual RNA molecules that are in various conformational states under near physiological solution conditions for the first time.
Jienyu Ding, Yun-Tzai Lee, Yuba Bhandari, Charles D. Schwieters, Lixin Fan, Ping Yu, Sergey G. Tarosov, Jason R. Stagno, Buyong Ma, Ruth Nussinov, Alan Rein, Jinwei Zhang, Yun-Xing Wang   +12 more
doaj   +1 more source

The Landscape of Virus-Host Protein–Protein Interaction Databases

Frontiers in Microbiology, 2022
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
doaj   +1 more source