Results 91 to 100 of about 4,559,139 (173)

T‐Cell Remodeling in Renal Fibrosis: From Acute Injury to Chronic Kidney Disease

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This Review presents renal fibrosis as a sequence of overlapping T‐cell programs, from chemokine‐guided recruitment and metabolic activation to maladaptive polarization, tertiary lymphoid structure formation, tissue residency, exhaustion, and senescence.
Qianhui Li, Junting Guan, Yifan Song, Hongxia Yang, Guangtao Li, Xiaodong Zhao, Jiaxin Liu, Bin Liu, Yang Tan, Honglan Zhou, Yang‐He Zhang, Yishu Wang   +11 more
wiley   +1 more source

NEW APPROCHES TO THE REMOVAL OF PROTEIN-BOUND TOXINS FROM BLOOD PLASM OF UREMIC PATIENTS [PDF]

, 2018
The article is elucidates the theoretical aspects of the effective method development for the removal of protein-bound uremic toxins. It is shown that the methods of flow and differential scanning microcalorimetry are effective for the evaluation of the
Sarnatskaya, V. V.
core  

Uremic Toxins and Atrial Fibrillation: Mechanisms and Therapeutic Implications

, 2019
Atrial fibrillation (AF) is the most prevalent arrhythmia in the general population. There is a close association between chronic kidney disease (CKD) and AF.
Masaki Ieda, Fumi Yamagami, Kazuko Tajiri, Dai Yumino   +3 more
core   +1 more source

Interaction analysis between patients with different CKD and liver cirrhosis stages for protein-bound uremic toxins by Least Squares Means.

, 2015
Interaction analysis between patients with different CKD and liver cirrhosis stages for protein-bound uremic toxins by Least Squares Means.
Cheng-Jui Lin (769644), Pei-Chen Wu (141736), Fang-Ju Sun (781650), Chi-Feng Pan (781649), Chih-Jen Wu (769646), Han-Hsiang Chen (781652), Hsuan-Liang Liu (781651), Tai-Cherng Liou (735030)   +7 more
core   +1 more source

Assessment of Within- and Inter-Patient Variability of Uremic Toxin Concentrations in Children with CKD

Toxins
To promote improved trial design in upcoming randomized clinical trials in childhood chronic kidney disease (CKD), insight in the within- and inter-patient variability of uremic toxins with its nutritional, treatment- and patient-related confounding ...
Evelien Snauwaert, Stefanie De Buyser, An Desloovere, Wim Van Biesen, Ann Raes, Griet Glorieux, Laure Collard, Koen Van Hoeck, Maria Van Dyck, Nathalie Godefroid, Johan Vande Walle, Sunny Eloot   +11 more
doaj   +1 more source

Urine levels of protein-bound uremic toxins (A) T-IS, (B) T-PCS in an animal model with liver failure (*:p<0.05) (N = 5).

, 2015
Urine levels of protein-bound uremic toxins (A) T-IS, (B) T-PCS in an animal model with liver failure ...
Cheng-Jui Lin (769644), Pei-Chen Wu (141736), Fang-Ju Sun (781650), Chi-Feng Pan (781649), Chih-Jen Wu (769646), Han-Hsiang Chen (781652), Hsuan-Liang Liu (781651), Tai-Cherng Liou (735030)   +7 more
core   +1 more source

Gamma-tocopherol vitamin E enhances the cytotoxicity of p-cresyl sulfate to renal tubular cells

European Journal of Medical Research
Background The protein-bound uremic toxins p-cresyl sulfate (PCS) and indoxyl sulfate (IS) are commonly found at elevated levels in patients with chronic kidney disease and can promote oxidative stress leading to the progression of renal disease. However,
Chyou-Wei Wei, Lin Jian, Shu-Cing Wu, Yi-Lin Chen, Ying-Ru Pan, Yi-Chung Chien, Jia-Yan Wu, Yung-Luen Yu, Giou-Teng Yiang   +8 more
doaj   +1 more source

Exploring Protein Binding of Uremic Toxins in Patients with Different Stages of Chronic Kidney Disease and during Hemodialysis

Toxins, 2015
As protein binding of uremic toxins is not well understood, neither in chronic kidney disease (CKD) progression, nor during a hemodialysis (HD) session, we studied protein binding in two cross-sectional studies.
Olivier Deltombe, Wim Van Biesen, Griet Glorieux, Ziad Massy, Annemieke Dhondt, Sunny Eloot   +5 more
doaj   +1 more source

Serum levels of protein-bound uremic toxins (A) T-IS, (B) T-PCS in an animal model with liver failure (*:p<0.01, #:p = 0.17) (N = 5).

, 2015
Serum levels of protein-bound uremic toxins (A) T-IS, (B) T-PCS in an animal model with liver failure ...
Cheng-Jui Lin (769644), Pei-Chen Wu (141736), Fang-Ju Sun (781650), Chi-Feng Pan (781649), Chih-Jen Wu (769646), Han-Hsiang Chen (781652), Hsuan-Liang Liu (781651), Tai-Cherng Liou (735030)   +7 more
core   +1 more source

From bench to the hemodialysis clinic: protein-bound uremic toxins modulate NF-\kappaB/Nrf2 expression

, 2017
International audiencePURPOSE: Uremic toxins produced by gut microbiota (indoxyl sulfate-IS, p-cresyl sulfate-p-CS, and indole-3-acetic acid-IAA) accumulate in hemodialysis (HD) patients and exhibit potent inflammatory effects.
Cardozo, Ludmila F. M. F., Denis Fouque, Mafra, Denise, Nakao, Lia S., Denise Mafra, Milena B. Stockler-Pinto, Borges, Natália A., Ludmila F. M. F. Cardozo, Fouque, Denis, Dolenga, Carla J., Natália A. Borges, Roberto Pecoits-Filho, Soulage, Christophe, Pecoits-Filho, Roberto, Christophe O. Soulage, Stockler-Pinto, Milena B., Lia S. Nakao, Carla J. Dolenga   +17 more
core   +1 more source