Results 101 to 110 of about 15,339 (215)

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, EarlyView.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Comparison of uremic toxin removal between expanded hemodialysis and high volume online hemodiafiltrations in different modes

Acta Biochimica Polonica
Various high-efficiency hemodialysis techniques exist, including different online high- volume hemodiafiltration (HDF) modes and expanded hemodialysis (HDx) utilizing dialyzers with medium cut-off (MCO) membranes.
Jan Biedunkiewicz, Agnieszka Zakrzewska, Sylwia Małgorzewicz, Michał Komorniczak, Katarzyna Jasiulewicz, Natalia Płonka, Agnieszka Tarasewicz, Magdalena Jankowska, Bogdan Biedunkiewicz, Alicja Dębska‐Ślizień, Leszek Tylicki   +10 more
doaj   +1 more source

Cardiorenal disease connection during post-menopause: The protective role of estrogen in uremic toxins induced microvascular dysfunction [PDF]

, 2017
Female gender, post-menopause, chronic kidney disease (CKD) and (CKD linked) microvascular disease are important risk factors for developing heart failure with preserved ejection fraction (HFpEF).
Asselbergs, F.W. (Folkert), Cheng, C. (Caroline), Duncker, D.J.G.M. (Dirk), Harakalova, M. (Magdalena), Pasterkamp, G. (Gerard), Pei, J. (Jiayi), Ruijter, H.M. (Hester ) den, Verhaar, M.C. (Marianne)   +7 more
core   +5 more sources

Machine learning‐based predictive models versus traditional risk scores in hemodialysis patients with comorbid urolithiasis

Precision Medical Sciences, EarlyView.
Machine learning‐based predictive models outperform traditional risk scores in hemodialysis patients with comorbid urolithiasis by capturing nonlinear, dialysis‐specific interactions. These approaches enable more accurate prediction of stone recurrence, sepsis, hospitalization, and mortality, supporting personalized risk stratification and precision ...
Dipal Chaulagain, Muhammad Riaz, Mirza Muhammad Hadeed Khawar, Jawad Hameed, Malik Sohail Riaz   +4 more
wiley   +1 more source

Vasculopathy in the setting of cardiorenal syndrome: roles of protein-bound uremic toxins [PDF]

American Journal of Physiology-Heart and Circulatory Physiology, 2017
Chronic kidney disease (CKD) often leads to and accelerates the progression of cardiovascular disease (CVD), while CVD also causes kidney dysfunction. This bidirectional interaction leads to the development of a complex syndrome known as cardiorenal syndrome (CRS). CRS not only involves both the heart and the kidney but also the vascular system through
Jingbin, Guo, Lu, Lu, Yue, Hua, Kevin, Huang, Ian, Wang, Li, Huang, Qiang, Fu, Aihua, Chen, Paul, Chan, Huimin, Fan, Zhong-Min, Liu, Bing Hui, Wang   +11 more
openaire   +2 more sources

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Prognostic value of contrast‐enhanced ultrasound in dogs with acute renal injury treated with haemodialysis

Veterinary Record, Volume 196, Issue 6, 15/22 March 2025.
Abstract Background It is clinically relevant to predict outcomes in dogs with acute kidney injury (AKI) treated with haemodialysis. The aim of this study was to evaluate the prognostic value of contrast‐enhanced ultrasound (CEUS) and its role in discriminating between AKI and acute impairment associated with chronic kidney disease (AKI/CKD).
Caterina Puccinelli, Ilaria Lippi, Tina Pelligra, Simonetta Citi   +3 more
wiley   +1 more source

An In Vitro System for Studying Toxin Transport Across Hemodialysis Membranes

Artificial Organs, EarlyView.
Development of an in vitro hemodialysis (HD) system based on mini dialyzers for evaluating hemodialysis membranes under physiologically relevant conditions. ABSTRACT Background Healthy kidneys regulate acid–base balance and electrolytes, produce hormones, and clear excess fluids and uremic toxins.
M. Torrents‐Yeste, D. Ramada, O. E. M. ter Beek, F. Pel, J. de Vries, B. H. Lentferink, K. G. F. Gerritsen, D. Stamatialis   +7 more
wiley   +1 more source

Research advances in the mechanisms of indoxyl sulfate and sarcopenia in chronic kidney disease

Linchuang shenzangbing zazhi
Sarcopenia in chronic kidney disease （CKD） occurs mainly in patients with end-stage renal disease （ESRD） on hemodialysis. The potential causes are insufficient nutrition intake, protein and energy consumption, inflammatory cytokines, oxidative stress ...
Shu-yuan Yang, Yan Zhang, Yan-kun Luo
doaj   +1 more source

The relevance of α-KLOTHO to the central nervous system: Some key questions [PDF]

, 2017
α-Klotho is well described as an anti-aging protein, with critical roles in kidney function as a transmembrane co-receptor for FGF23, and as a soluble factor in serum.
Berwick, Daniel Charles, Cararo-Lopes, Marina Minto, Kawamoto, Elisa Mitiko, Mazucanti, Caio Henrique Yokoyama, Scavone, Cristoforo   +4 more
core   +1 more source