Results 11 to 20 of about 2,237,588 (315)

Identification of photocrosslinking peptide ligands by mRNA display

open access: yesCommunications Chemistry, 2023
Photoaffinity labelling is a promising method for studying protein-ligand interactions. However, obtaining a specific, efficient crosslinker can require significant optimisation.
Yuteng Wu   +5 more
doaj   +1 more source

Developing methods to study conformational changes in RNA crystals using a photocaged ligand

open access: yesFrontiers in Molecular Biosciences, 2022
Crystallographic observation of structural changes in real time requires that those changes be uniform both spatially and temporally. A primary challenge with time-resolved ligand-mixing diffraction experiments is asynchrony caused by variable factors ...
Hyun Kyung Lee   +8 more
doaj   +1 more source

Increased Pentraxin 3 Levels Correlate With IVIG Responsiveness and Coronary Artery Aneurysm Formation in Kawasaki Disease

open access: yesFrontiers in Immunology, 2021
Kawasaki disease (KD) is a febrile disease of childhood characterized by systemic vasculitis that can lead to coronary artery lesions (CAL). This was a prospective cohort study to determine the levels of the pentraxin 3 (PTX3), soluble CD24-Subtype ...
Toshiyuki Kitoh   +11 more
doaj   +1 more source

Visualizing RNA conformational and architectural heterogeneity in solution

open access: yesNature Communications, 2023
RNA conformational heterogeneity is important to diverse functions. Here, the authors use AFM to directly visualize individual RNA molecules that are in various conformational states under near physiological solution conditions for the first time.
Jienyu Ding   +12 more
doaj   +1 more source

Transient protein-protein interactions [PDF]

open access: yesProtein Engineering Design and Selection, 2011
Transient complexes are crucial for diverse biological processes such as biochemical pathways and signaling cascades in the cell. Here, we give an overview of the transient interactions; the importance of transient interactions as drug targets; and the structural characterization of transient protein-protein complexes based on the geometrical and ...
Saliha Ece, Acuner Ozbabacan   +3 more
openaire   +2 more sources

Protein-protein interaction. [PDF]

open access: yes, 2022
STRING software depicts the protein-protein interaction network of XRCC2, XRCC3 and RAD51. The first ten proteins that primarily interacts with XRCC2, XRCC3 and RAD51 is highlighted.
Nageswara Rao Dunna (11985969)   +5 more
core   +1 more source

Protein–protein interactions

open access: yesCurrent Opinion in Structural Biology, 2013
We are proud to present the first edition of the Protein–protein interactions Section of Current Opinion in Structural Biology. The Section is new, but the topic has been present in the journal from the very start. Volume 1, Issue 1, dated February 1991, had a review by Janin entitled Protein–protein interactions and assembly, and others by Bode and ...
Janin, Joel, Bonvin, Alexandre M. J. J.
openaire   +4 more sources

The Landscape of Virus-Host Protein–Protein Interaction Databases

open access: yesFrontiers in Microbiology, 2022
Knowledge of virus-host interactomes has advanced exponentially in the last decade by the use of high-throughput screening technologies to obtain a more comprehensive landscape of virus-host protein–protein interactions.
Gabriel Valiente
doaj   +1 more source

Aquaporin Protein-Protein Interactions [PDF]

open access: yesInternational Journal of Molecular Sciences, 2017
Aquaporins are tetrameric membrane-bound channels that facilitate transport of water and other small solutes across cell membranes. In eukaryotes, they are frequently regulated by gating or trafficking, allowing for the cell to control membrane permeability in a specific manner.
Jennifer Roche   +1 more
openaire   +2 more sources

AT2 receptor interacting protein 1 (ATIP1) mediates COX-2 induction by an AT2 receptor agonist in endothelial cells

open access: yesBiochemistry and Biophysics Reports, 2020
Angiotensin II (Ang II) type 2 receptor (AT2R) is one of the major components of the renin-angiotensin-aldosterone system. Nevertheless, the physiological role is not well defined compared to the understanding of the Ang II type 1 receptor (AT1R), which ...
Keita Soda   +3 more
doaj   +1 more source

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