STRING and STITCH: known and predicted interactions between proteins and chemicals [PDF]
, 2008 Information on protein-protein and protein-chemical interactions is essential for understanding cellular functions. The STRING and STITCH web resources integrate interaction evidence derived from pathways, automatic literature mining, primary ...
Christian von Mering +5 more
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ProDGe: investigating protein-protein interactions at the domain level [PDF]
, 2011 An important goal of systems biology is the identification and investigation of known and predicted protein-protein interactions to obtain more information about new cellular pathways and processes.
Adrian Schrö +5 more
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Molecular Systems Biology, 2015 Mitogen‐activated protein kinases (MAPK) are broadly used regulators of cellular signaling. However, how these enzymes can be involved in such a broad spectrum of physiological functions is not understood.
András Zeke +8 more
doaj +1 more source
Predicting protein phenotypes based on protein-protein interaction network. [PDF]
PLoS ONE, 2011 BackgroundIdentifying associated phenotypes of proteins is a challenge of the modern genetics since the multifactorial trait often results from contributions of many proteins.
Lele Hu +3 more
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Relation Extraction of Protein Complexes from Dynamic Protein-Protein Interaction Network [PDF]
Journal of Biomedical Physics and Engineering, 2021 Background: Dynamic protein-protein interaction networks (DPPIN) can confirm the conditional and temporal features of proteins and protein complexes. In addition, the relation of protein complexes in dynamic networks can provide useful information in ...
Moslem Mohammadi Jenghara +2 more
doaj +1 more source
DCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction
BMC Genomics, 2022 Background Protein-protein interaction (PPI) is very important for many biochemical processes. Therefore, accurate prediction of PPI can help us better understand the role of proteins in biochemical processes.
Wenqi Chen +5 more
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Memory in repetitive protein–protein interaction series
APL Bioengineering, 2023 Interactions between proteins coordinate biological processes in an organism and may impact its responses to changing environments and diseases through feedback systems. Feedback systems function by using changes in the past to influence behaviors in the
Aaron M. Rosado +8 more
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Hierarchical graph learning for protein–protein interaction
Nature Communications, 2023 Despite recent progress, machine learning methods remain inadequate in modeling the natural protein-protein interaction (PPI) hierarchy for PPI prediction.
Ziqi Gao +8 more
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Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family [PDF]
, 2016 Posttranslational regulation of protein function is an ubiquitous mechanism in eukaryotic cells. Here, we analyzed biological properties of nodes and edges of a human protein-protein interaction phosphorylation-based network, especially of those nodes ...
Bustos, Diego Martin +2 more
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Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]
, 2018 Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan +10 more
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