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Analysis of leukocyte membrane protein interactions using protein microarrays [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Foster-Cuevas, M +18 more
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Protein-Protein Interactions in Plants [PDF]
The study of protein-protein interactions (PPIs) is essential to uncover unknown functions of proteins at the molecular level and to gain insight into complex cellular networks. Affinity purification and mass spectrometry (AP-MS), yeast two-hybrid, imaging approaches and numerous diverse databases have been developed as strategies to analyze PPIs.
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Length, protein–protein interactions, and complexity [PDF]
13 pages, 5 figures, 2 tables, to appear in Physica ...
Tan, T. +3 more
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A web-based protein interaction network visualizer [PDF]
Background Interaction between proteins is one of the most important mechanisms in the execution of cellular functions. The study of these interactions has provided insight into the functioning of an organism’s processes.
Holifidy A Rapanoël +11 more
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Discovering functional interaction patterns in protein-protein interaction networks
Background In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of genes and/or proteins of an increasing number of organisms.
Can Tolga, Turanalp Mehmet E
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Protein-protein interaction hotspots carved into sequences. [PDF]
Protein-protein interactions, a key to almost any biological process, are mediated by molecular mechanisms that are not entirely clear. The study of these mechanisms often focuses on all residues at protein-protein interfaces.
Yanay Ofran, Burkhard Rost
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ProDGe: investigating protein-protein interactions at the domain level [PDF]
An important goal of systems biology is the identification and investigation of known and predicted protein-protein interactions to obtain more information about new cellular pathways and processes.
Andreas Dräger +8 more
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ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
PTOMSM: A modified version of Topological Overlap Measure used for predicting Protein-Protein Interaction Network [PDF]
A variety of methods are developed to integrating diverse biological data to predict novel interaction relationship between proteins. However, traditional integration can only generate protein interaction pairs within existing relationships.
Xun Huang
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Covalent drugs can achieve high potency with long dosing intervals. However, concerns remain about side-effects associated with off-target reactivity.
Isabel R. Mathiesen +3 more
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