Results 51 to 60 of about 2,229,273 (315)

The Arginine-Rich Motif of Bamboo mosaic virus Satellite RNA-Encoded P20 Mediates Self-Interaction, Intracellular Targeting, and Cell-to-Cell Movement

Molecular Plant-Microbe Interactions, 2006
Satellite RNA of Bamboo mosaic virus (satBaMV) has a single open reading frame for a nonstructural, RNA-binding protein, P20, which facilitates the long-distance movement of satBaMV in Nicotiana benthamiana.
Paramasivan Vijaya Palani, Venkatraman Kasiviswanathan, Jeff Chien-Fu Chen, Wei Chen, Yau-Heiu Hsu, Na-Sheng Lin   +5 more
doaj   +1 more source

Protein-protein interaction of Lupus

, 2020
Protein-protein interaction and biomarkers in ...
Danish Rehan (5608505), Rosalind Silverman (5253824), Lorelei Silverman (5205368)   +2 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Challenges and opportunities in technologies and methods for lncRNA structure determination

Cell & Bioscience
Long non-coding RNAs (lncRNAs) play pivotal roles in diverse cellular processes ranging from gene regulation and chromatin remodeling to RNA stability and epigenetic modifications. Despite the identification of approximately 95,000 lncRNA genes in humans,
Maximilia Frazao De Souza Degenhardt, Yun-Xing Wang   +1 more
doaj   +1 more source

Protein-protein interaction hotspots carved into sequences. [PDF]

PLoS Computational Biology, 2007
Protein-protein interactions, a key to almost any biological process, are mediated by molecular mechanisms that are not entirely clear. The study of these mechanisms often focuses on all residues at protein-protein interfaces.
Yanay Ofran, Burkhard Rost
doaj   +1 more source

Principles of protein-protein interactions [PDF]

Bioinformatics, 2002
Abstract In the postgenomic era, one of the most interesting and important challenges is to understand protein interactions on a large scale. The physical interactions between protein domains are fundamental to the workings of a cell: in multi-domain polypeptide chains, in multi-subunit proteins and in transient complexes between ...
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Discover protein sequence signatures from protein-protein interaction data

BMC Bioinformatics, 2005
Background The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-protein interaction (PPI) datasets.
Haasl Ryan J, Fang Jianwen, Dong Yinghua, Lushington Gerald H   +3 more
doaj   +1 more source

AligNet: alignment of protein-protein interaction networks

BMC Bioinformatics, 2020
Background All molecular functions and biological processes are carried out by groups of proteins that interact with each other. Metaproteomic data continuously generates new proteins whose molecular functions and relations must be discovered.
Adrià Alcalá, Ricardo Alberich, Mercè Llabrés, Francesc Rosselló, Gabriel Valiente   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source