Results 51 to 60 of about 3,268,890 (286)

Discover protein sequence signatures from protein-protein interaction data

open access: yesBMC Bioinformatics, 2005
Background The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-protein interaction (PPI) datasets.
Haasl Ryan J   +3 more
doaj   +1 more source

AligNet: alignment of protein-protein interaction networks

open access: yesBMC Bioinformatics, 2020
Background All molecular functions and biological processes are carried out by groups of proteins that interact with each other. Metaproteomic data continuously generates new proteins whose molecular functions and relations must be discovered.
Adrià Alcalá   +4 more
doaj   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

SPRINT: Ultrafast protein-protein interaction prediction of the entire human interactome

open access: yes, 2017
Proteins perform their functions usually by interacting with other proteins. Predicting which proteins interact is a fundamental problem. Experimental methods are slow, expensive, and have a high rate of error.
Ilie, Lucian, Li, Yiwei
core   +1 more source

The Relationship between the UniProt Knowledgebase (UniProtKB) and the IntAct Molecular Interaction Databases [PDF]

open access: yes, 2009
IntAct provides a freely available, open source database system and analysis tools for protein interaction data. All interactions are derived from literature curation or direct user submission and all experimental information relating to binary protein ...
Yasmin Alam-Faruque
core   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

The protein-protein interaction ontology: for better representing and capturing the biological context of protein interaction

open access: yesBMC Genomics, 2021
Background With the rapid increase in the amount of Protein-Protein Interaction (PPI) data, the establishment of an event-centered PPI ontology that contains temporal and spatial vocabularies is urgently needed to clarify PPI biological annotations.
Mansheng Li   +6 more
doaj   +1 more source

Benchmark Evaluation of Protein–Protein Interaction Prediction Algorithms

open access: yesMolecules, 2021
Protein–protein interactions (PPIs) perform various functions and regulate processes throughout cells. Knowledge of the full network of PPIs is vital to biomedical research, but most of the PPIs are still unknown.
Brandan Dunham, Madhavi K. Ganapathiraju
doaj   +1 more source

Preferential attachment in the protein network evolution

open access: yes, 2003
The Saccharomyces cerevisiae protein-protein interaction map, as well as many natural and man-made networks, shares the scale-free topology. The preferential attachment model was suggested as a generic network evolution model that yields this universal ...
A. Vazquez   +8 more
core   +1 more source

Poly(amidoamine)s synthesis, characterisation and interaction with BSA [PDF]

open access: yes, 2014
Cationic poly(amidoamine)s (PAAs) were synthesised and characterised by NMR and gel permeation chromatography. Their thermal properties were investigated using thermogravimetric analysis and differential scanning calorimetry.
Akinc   +45 more
core   +1 more source

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