Results 71 to 80 of about 8,952,616 (310)
Deep learning frameworks for protein–protein interaction prediction
Computational and Structural Biotechnology Journal, 2022 Protein-protein interactions (PPIs) play key roles in a broad range of biological processes. The disorder of PPIs often causes various physical and mental diseases, which makes PPIs become the focus of the research on disease mechanism and clinical ...
Xiaotian Hu +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BMC Genomics, 2021 Background With the rapid increase in the amount of Protein-Protein Interaction (PPI) data, the establishment of an event-centered PPI ontology that contains temporal and spatial vocabularies is urgently needed to clarify PPI biological annotations.
Mansheng Li +6 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Protein-Protein interaction in Obstructive Sleep Apnea.docx
, 2019 study analyzing the protein-protein interaction in patients with obstructive sleep apnea through high-throughput cell biology ...
Rosalind Silverman (5253824) +2 more
core +1 more source
AligNet: alignment of protein-protein interaction networks
BMC Bioinformatics, 2020 Background All molecular functions and biological processes are carried out by groups of proteins that interact with each other. Metaproteomic data continuously generates new proteins whose molecular functions and relations must be discovered.
Adrià Alcalá +4 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
An artificial immune system for clustering amino acids in the context of protein function classification [PDF]
, 2009 This paper addresses the classification task of data mining (a form of supervised learning) in the context of an important bioinformatics problem, namely the prediction of protein functions.
Timmis, Jon +5 more
core +1 more source
Protein-protein interaction (PPI) network of identified RNAi-related genes based on STRING database.
, 2023 Protein-protein interaction (PPI) network of identified RNAi-related genes based on STRING database.
Afsana Yeasmin Mim (16274685) +4 more
core +1 more source
Influence of protein abundance on high-throughput protein-protein interaction detection. [PDF]
PLoS ONE, 2009 Experimental protein-protein interaction (PPI) networks are increasingly being exploited in diverse ways for biological discovery. Accordingly, it is vital to discern their underlying natures by identifying and classifying the various types of ...
Joseph Ivanic +3 more
doaj +1 more source