Results 81 to 90 of about 8,552,186 (306)

Phospho‐tyrosine dependent protein–protein interaction network

Molecular Systems Biology, 2015
Post‐translational protein modifications, such as tyrosine phosphorylation, regulate protein–protein interactions (PPIs) critical for signal processing and cellular phenotypes.
Arndt Grossmann, Nouhad Benlasfer, Petra Birth, Anna Hegele, Franziska Wachsmuth, Luise Apelt, Ulrich Stelzl   +6 more
doaj   +1 more source

MEGADOCK-Web: an integrated database of high-throughput structure-based protein-protein interaction predictions

BMC Bioinformatics, 2018
Background Protein-protein interactions (PPIs) play several roles in living cells, and computational PPI prediction is a major focus of many researchers.
Takanori Hayashi, Yuri Matsuzaki, Keisuke Yanagisawa, Masahito Ohue, Yutaka Akiyama   +4 more
doaj   +1 more source

SnapShot: Protein-Protein Interaction Networks

Cell, 2011
Methods MethodsYeast two-hybridProtein fragment complementationassayTranscription factor, ubiquitinDehydrofolate reductaseGFP or YFPProtein pairs+ Interacting- NoninteractingInteraction examples- Signaling- Enzyme - substrateInteraction strength-Transient to stableAffinity purification/Mass spectrometryBiochemical purification of affinity-tagged baits ...
Seebacher, Jan, Gavin Perrin, Anne-Claude   +1 more
openaire   +2 more sources

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Local pre-processing for node classification in networks : application in protein-protein interaction [PDF]

, 2013
Network modelling provides an increasingly popular conceptualisation in a wide range of domains, including the analysis of protein structure. Typical approaches to analysis model parameter values at nodes within the network. The spherical locality around
Ross, Isla, Foley, Christopher Eric, Wilson, John, Dufton, Mark, Al Azwari, Sana Mohammad M   +4 more
core   +4 more sources

A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation

Nature Communications
Peptidylarginine deiminase IV (PADI4, PAD4) deregulation promotes the development of autoimmunity, cancer, atherosclerosis and age-related tissue fibrosis.
M. Teresa Bertran, Robert Walmsley, Thomas Cummings, Iker Valle Aramburu, Donald J. Benton, Rocio Mora Molina, Jayalini Assalaarachchi, Maria Chasampalioti, Tessa Swanton, Dhira Joshi, Stefania Federico, Hanneke Okkenhaug, Lu Yu, David Oxley, Simon Walker, Venizelos Papayannopoulos, Hiroaki Suga, Maria A. Christophorou, Louise J. Walport   +18 more
doaj   +1 more source

Modularity detection in protein-protein interaction networks

BMC Research Notes, 2011
Background Many recent studies have investigated modularity in biological networks, and its role in functional and structural characterization of constituent biomolecules.
Narayanan Tejaswini, Gersten Merril, Subramaniam Shankar, Grama Ananth   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Non-Contiguous Protein Recombination [PDF]

, 2013
Swapping sequence elements among related proteins can produce chimeric proteins with novel behaviors and improved properties such as enhanced stability. Although homologous mutations are much more conservative than random mutations, chimeras of distantly-
Smith, Matthew Alexander
core   +1 more source

NOXclass: prediction of protein-protein interaction types

BMC Bioinformatics, 2006
Background Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level.
Sommer Ingolf, Domingues Francisco S, Zhu Hongbo, Lengauer Thomas   +3 more
doaj   +1 more source