Results 11 to 20 of about 3,948,731 (294)
Protein tyrosine kinases in Schistosoma mansoni [PDF]
Memorias do Instituto Oswaldo Cruz, 2006 The identification and description of signal transduction molecules and mechanisms are essential to elucidate Schistosoma mansoni host-parasite interactions and parasite biology.
Diana Bahia +4 more
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Microbial protein-tyrosine kinases. [PDF]
J Biol Chem, 2014 Microbial ester kinases identified in the past 3 decades came as a surprise, as protein phosphorylation on Ser, Thr, and Tyr amino acids was thought to be unique to eukaryotes. Current analysis of available microbial genomes reveals that "eukaryote-like" protein kinases are prevalent in prokaryotes and can converge in the same signaling pathway with ...
Chao JD, Wong D, Av-Gay Y.
europepmc +5 more sources
Tyrosine kinases in rheumatoid arthritis [PDF]
Journal of Inflammation, 2011 Rheumatoid arthritis (RA) is an inflammatory, polyarticular joint disease. A number of cellular responses are involved in the pathogenesis of rheumatoid arthritis, including activation of inflammatory cells and cytokine expression. The cellular responses
Kobayashi Akiko, Okamoto Hiroshi
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BY-kinases: Protein tyrosine kinases like no other. [PDF]
J Biol Chem, 2023 BY-kinases (for bacterial tyrosine kinases) constitute a family of protein tyrosine kinases that are highly conserved in the bacterial kingdom and occur most commonly as essential components of multicomponent assemblies responsible for the biosynthesis, polymerization, and export of complex polysaccharides involved in biofilm or capsule formation.
Hajredini F, Alphonse S, Ghose R.
europepmc +3 more sources
Repurposing Tyrosine Kinase Inhibitors for Sickle Cell Disease: Focus on Band 3 Phosphorylation [PDF]
BiomedicinesSickle cell disease (SCD) is an autosomal recessive hemoglobin disorder that is mainly characterized by the presence of hemoglobin S (HbS; point mutation [Glu6Val] in the beta-globin gene). Under deoxygenated conditions, HbS polymerizes and serves as the
Raj Gupta +3 more
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Protein Tyrosine Kinases: Their Roles and Their Targeting in Leukemia. [PDF]
Cancers (Basel), 2021 K Bhanumathy K +5 more
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The dictyostelium kinome--analysis of the protein kinases from a simple model organism. [PDF]
PLoS Genetics, 2006 Dictyostelium discoideum is a widely studied model organism with both unicellular and multicellular forms in its developmental cycle. The Dictyostelium genome encodes 285 predicted protein kinases, similar to the count of the much more advanced ...
Jonathan M Goldberg +6 more
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Exploration of Immunology, 2023 The growth and differentiation of normal cells are controlled by protein-tyrosine kinases, which serve as receptors for a wide variety of external signals.
Shulamit Katzav
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PTB domain-directed substrate targeting in a tyrosine kinase from the unicellular choanoflagellate Monosiga brevicollis. [PDF]
PLoS ONE, 2011 Choanoflagellates are considered to be the closest living unicellular relatives of metazoans. The genome of the choanoflagellate Monosiga brevicollis contains a surprisingly high number and diversity of tyrosine kinases, tyrosine phosphatases, and ...
Victoria Prieto-Echagüe +4 more
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Development of the Sensing Platform for Protein Tyrosine Kinase Activity
Biosensors, 2021 A miniature tyrosinase-based electrochemical sensing platform for label-free detection of protein tyrosine kinase activity was developed in this study. The developed miniature sensing platform can detect the substrate peptides for tyrosine kinases, such ...
Lan-Yi Wei +5 more
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