Results 21 to 30 of about 15,507,347 (338)
UniProt: the Universal Protein Knowledgebase in 2023
Nucleic Acids Res., 2022 The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information.A. Bateman, M. Martin, S. Orchard, M. Magrane, Shadab Ahmad, E. Alpi, E. Bowler-Barnett, R. Britto, Hema Bye-A-Jee, Austra Cukura, Paul Denny, Tunca Dogan, Thankgod Ebenezer, Jun Fan, Penelope Garmiri, Leonardo Jose da Costa Gonzales, E. Hatton-Ellis, Abdulrahman Hussein, A. Ignatchenko, Giuseppe Insana, Rizwan Ishtiaq, Vishal Joshi, D. Jyothi, Swaathi Kandasaamy, A. Lock, Aurélien Luciani, Marija Lugarić, Jie Luo, Yvonne Lussi, Alistair MacDougall, F. Madeira, Mahdi Mahmoudy, Alok Mishra, Katie Moulang, Andrew Nightingale, Sangya Pundir, G. Qi, Shriya Raj, P. Raposo, Daniel L Rice, Rabie Saidi, Rafael Santos, Elena Speretta, J. Stephenson, Prabhat Totoo, Edward Turner, N. Tyagi, Preethi Vasudev, Kate Warner, Xavier Watkins, Rossana Zaru, H. Zellner, A. Bridge, L. Aimo, Ghislaine Argoud-Puy, A. Auchincloss, K. Axelsen, Parit Bansal, Delphine Baratin, Teresa M Batista Neto, M. Blatter, Jerven T. Bolleman, E. Boutet, L. Breuza, B. Gil, Cristina Casals-Casas, Kamal Chikh Echioukh, E. Coudert, Béatrice A. Cuche, Edouard de Castro, A. Estreicher, M. Famiglietti, M. Feuermann, E. Gasteiger, P. Gaudet, S. Gehant, V. Gerritsen, A. Gos, N. Gruaz, C. Hulo, Nevila Hyka-Nouspikel, F. Jungo, A. Kerhornou, Philippe le Mercier, D. Lieberherr, P. Masson, A. Morgat, Venkatesh Muthukrishnan, S. Paesano, I. Pedruzzi, S. Pilbout, L. Pourcel, S. Poux, Monica Pozzato, Manuela Pruess, Nicole Redaschi, C. Rivoire, Christian J. A. Sigrist, K. Sonesson, S. Sundaram, Cathy H. Wu, C. Arighi, L. Arminski, Chuming Chen, Yongxing Chen, Hongzhan Huang, K. Laiho, P. McGarvey, D. Natale, K. Ross, C. R. Vinayaka, Qinghua Wang, Yuqi Wang, Jian Zhang +113 moresemanticscholar +1 more sourceA human bispecific antibody neutralizes botulinum neurotoxin serotype A
Scientific Reports, 2023 Botulinum neurotoxin (BoNT) shows high lethality and toxicity, marking it as an important biological threat. The only effective post-exposure therapy is botulinum antitoxin; however, such products have great potential for improvement. To prevent or treat Jiansheng Lu, Yujia Jiang, Jiazheng Guo, Lei Chen, Fujia Liu, Zhiying Li, Xuyang Liu, Peng Du, Yunzhou Yu, Rong Wang, Zhixin Yang +10 moredoaj +1 more sourceUniProt: the universal protein knowledgebase in 2021
Nucleic Acids Res., 2020 The aim of the UniProt Knowledgebase is to provide users with a comprehensive, high-quality and freely accessible set of protein sequences annotated with functional information.A. Bateman, M. Martin, S. Orchard, M. Magrane, Rahat Agivetova, Shadab Ahmad, E. Alpi, E. Bowler-Barnett, R. Britto, Borisas Bursteinas, Hema Bye-A-Jee, Ray Coetzee, Austra Cukura, Alan W. Sousa da Silva, P. Denny, Tunca Dogan, Thankgod Ebenezer, Jun Fan, Leyla Jael García Castro, Penelope Garmiri, G. Georghiou, Leonardo Gonzales, E. Hatton-Ellis, Abdulrahman Hussein, A. Ignatchenko, Giuseppe Insana, Rizwan Ishtiaq, Petteri Jokinen, Vishal Joshi, D. Jyothi, A. Lock, R. Lopez, Aurélien Luciani, Jie Luo, Yvonne Lussi, Alistair MacDougall, F. Madeira, Mahdi Mahmoudy, Manuela Menchi, A. Mishra, Katie Moulang, Andrew Nightingale, C. Oliveira, Sangya Pundir, G. Qi, Shriya Raj, Daniel L Rice, M. Rodríguez-López, Rabie Saidi, Joseph Sampson, T. Sawford, Elena Speretta, Edward Turner, N. Tyagi, Preethi Vasudev, V. Volynkin, Kate Warner, Xavier Watkins, Rossana Zaru, H. Zellner, A. Bridge, S. Poux, Nicole Redaschi, L. Aimo, Ghislaine Argoud-Puy, A. Auchincloss, K. Axelsen, Parit Bansal, Delphine Baratin, M. Blatter, Jerven T. Bolleman, E. Boutet, L. Breuza, Cristina Casals-Casas, E. D. Castro, Kamal Chikh Echioukh, E. Coudert, Béatrice A. Cuche, M. Doche, D. Dornevil, A. Estreicher, M. Famiglietti, M. Feuermann, E. Gasteiger, S. Gehant, Vivienne Baillie Gerritsen, A. Gos, N. Gruaz-Gumowski, U. Hinz, C. Hulo, Nevila Hyka-Nouspikel, F. Jungo, G. Keller, A. Kerhornou, V. Lara, P. L. Mercier, D. Lieberherr, T. Lombardot, X. Martin, P. Masson, A. Morgat, T. Neto, S. Paesano, I. Pedruzzi, S. Pilbout, L. Pourcel, Monica Pozzato, Manuela Pruess, C. Rivoire, Christian J. A. Sigrist, K. Sonesson, A. Stutz, S. Sundaram, M. Tognolli, L. Verbregue, Cathy H. Wu, C. Arighi, L. Arminski, Chuming Chen, Yongxing Chen, J. Garavelli, Hongzhan Huang, K. Laiho, P. McGarvey, D. Natale, K. Ross, C. R. Vinayaka, Qinghua Wang, Yuqi Wang, L. Yeh, Jian Zhang, Patrick Ruch, D. Teodoro +132 moresemanticscholar +1 more sourceEvolutionary-scale prediction of atomic level protein structure with a language model
bioRxiv, 2022 Artificial intelligence has the potential to open insight into the structure of proteins at the scale of evolution. It has only recently been possible to extend protein structure prediction to two hundred million cataloged proteins.Zeming Lin, Halil Akin, Roshan Rao, B. Hie, Zhongkai Zhu, Wenting Lu, Nikita Smetanin, Robert Verkuil, Ori Kabeli, Y. Shmueli, Allan dos Santos Costa, Maryam Fazel-Zarandi, Tom Sercu, Salvatore Candido, Alexander Rives +14 moresemanticscholar +1 more sourcePfam: The protein families database in 2021
Nucleic Acids Res., 2020 The Pfam database is a widely used resource for classifying protein sequences into families and domains. Since Pfam was last described in this journal, over 350 new families have been added in Pfam 33.1 and numerous improvements have been made to ...Jaina Mistry, S. Chuguransky, Lowri Williams, Matloob Qureshi, Gustavo A. Salazar, E. Sonnhammer, Silvio C. E. Tosatto, L. Paladin, Shriya Raj, Lorna J. Richardson, R. Finn, A. Bateman +11 moresemanticscholar +1 more sourceProteins, proteins everywhere [PDF]
Science, 2021 The first protein structures were determined by x-ray crystallography in 1957 by John C. Kendrew and Max F. Perutz. As a bioinorganic chemist, I was delighted that the structures were myoglobin and hemoglobin, both heme proteins with big, beautiful iron atoms.openaire +2 more sourcesCryo-EM structure of a functional monomeric Photosystem I from Thermosynechococcus elongatus reveals red chlorophyll cluster
Communications Biology, 2021 Çoruh, Frank et al. report the structure of monomeric Photosystem I from cyanobacteria Thermosynechoccocus elongatus BP-1. They assign monomerization-induced loss of red chlorophylls to a cluster of chlorophylls adjacent to PsaX.Orkun Çoruh, Anna Frank, Hideaki Tanaka, Akihiro Kawamoto, Eithar El-Mohsnawy, Takayuki Kato, Keiichi Namba, Christoph Gerle, Marc M. Nowaczyk, Genji Kurisu +9 moredoaj +1 more sourceStructural mechanism of laminin recognition by integrin
Nature Communications, 2021 Recognition of laminin by integrin receptors mediates epithelial cell adhesion to basement membrane. Here, the structures of the α6β1 integrin alone and in complex with three-chain laminin-511 fragment reveal the laminin-integrin interface in molecular ...Takao Arimori, Naoyuki Miyazaki, Emiko Mihara, Mamoru Takizawa, Yukimasa Taniguchi, Carlos Cabañas, Kiyotoshi Sekiguchi, Junichi Takagi +7 moredoaj +1 more source
