Results 1 to 10 of about 7,628,689 (242)
Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation
Molecular & Cellular Proteomics, 2018 The phenomenon of protein aggregation capture (PAC) on a wide range of different microparticles is described. Exploiting this mechanism enables generation of clean peptide mixtures from cell lines, tissues, and protein pulldowns for proteomics ...
T. Batth +7 more
semanticscholar +1 more source
Jurnal Kimia Sains dan Aplikasi, 2020 Studies on the anti-aggregation of dithiothreitol (DTT) induced - protein is generally determined by the fraction soluble (non-aggregated) protein. While the turbidity method is commonly used in studies of anti-aggregation, in which protein is induced by
Amat Rifai +2 more
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CPAD, Curated Protein Aggregation Database: A Repository of Manually Curated Experimental Data on Protein and Peptide Aggregation. [PDF]
PLoS ONE, 2016 Accurate distinction between peptide sequences that can form amyloid-fibrils or amorphous β-aggregates, identification of potential aggregation prone regions in proteins, and prediction of change in aggregation rate of a protein upon mutation(s) are ...
A Mary Thangakani +5 more
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Chemical Physics Impact, 2022 Recent studies have indicated that tau protein aggregation is closely related to Alzheimer's disease. Though the later stages of the aggregation process are extensively studied, it is still unknown how the aggregation occurs in the earliest stage.
S. Roy Chowdhury, H. Peter Lu
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Protein aggregation linked to Alzheimer's disease revealed by saturation transfer MRI
NeuroImage, 2019 The goal of this study was to develop a molecular biomarker for the detection of protein aggregation involved in Alzheimer's disease (AD) by exploiting the features of the water saturation transfer spectrum (Z‐spectrum), the CEST signal of which is ...
Lin Chen +9 more
semanticscholar +1 more source
Kinetics of Thermal Denaturation and Aggregation of Bovine Serum Albumin. [PDF]
PLoS ONE, 2016 Thermal aggregation of bovine serum albumin (BSA) has been studied using dynamic light scattering, asymmetric flow field-flow fractionation and analytical ultracentrifugation. The studies were carried out at fixed temperatures (60°C, 65°C, 70°C and 80°C)
Vera A Borzova +9 more
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Toxic Tau Oligomers Modulated by Novel Curcumin Derivatives [PDF]
, 2019 The pathological aggregation and accumulation of tau, a microtubule-associated protein, is a common feature amongst more than 18 different neurodegenerative diseases that are collectively known as tauopathies.
Bucchieri, Fabio +6 more
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The Contribution of Iron to Protein Aggregation Disorders in the Central Nervous System
Frontiers in Neuroscience, 2019 The homeostasis of iron is of fundamental importance in the central nervous system (CNS) to ensure biological processes such as oxygen transport, mitochondrial respiration or myelin synthesis.
Karina Joppe +3 more
semanticscholar +1 more source
Aggregation and conformational stability evaluation of myoglobin in the presence of ionic surfactant
Saudi Pharmaceutical Journal, 2018 Sodium lauroyl sarcosinate (SLS) is frequently used for the solubilization of inclusion bodies in vitro due to its structural similarity to lipid plasma membrane.
Mohammad A. Alsenaidy
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Protein aggregation in E. coli : short term and long term effects of nutrient density. [PDF]
PLoS ONE, 2014 During exponential growth some cells of E. coli undergo senescence mediated by asymmetric segregation of damaged components, particularly protein aggregates. We showed previously that functional cell division asymmetry in E.
Ulfat I Baig +3 more
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