Results 241 to 250 of about 4,101,523 (297)

Landscape of Protein Post-Translational Modifications in Age-Related Neurodegenerative Disorders: Implications in Protein Aggregation, Altered Cellular Processes, and Therapeutics. [PDF]

ACS Omega
Singh AK, Kundu TK.
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Kyphoscoliosis peptidase deficiency-induced myofibrillar degeneration, focal depletion of mitochondria, and protein aggregation: A true myofibrillar myopathy? [PDF]

J Neuromuscul Dis
Durmuş H, Clemen CS, Uçar EÖ, Hofmann A, Schlötzer-Schrehardt U, Mertoğlu E, Ceylaner S, Dursun M, Sewry CA, Schröder R, Parman Y.   +10 more
europepmc   +1 more source

Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration. [PDF]

Front Mol Neurosci
Varte V, Rincon-Limas DE.
europepmc   +1 more source

Reactive fluorescent probe for covalent membrane-anchoring: enabling real-time imaging of protein aggregation dynamics in live cells. [PDF]

Chem Sci
Wei H, Xu L, Wei K, Bian W, Wen Y, Yu W, Zhang H, Huang H, James TD, Sun X.   +9 more
europepmc   +1 more source

iPAR: a new reporter for eukaryotic cytoplasmic protein aggregation. [PDF]

BMC Methods
Lecinski S, Howard JAL, MacDonald C, Leake MC.   +3 more
europepmc   +1 more source

Mitofusin MFN2 acts as a molecular sensor preventing protein aggregation and mitophagy, with a protective effect against apoptosis in Charcot-Marie-Tooth type 2A disease. [PDF]

Autophagy Rep
Joaquim M, Dohrn MF, Chevrollier A, Escobar-Henriques M.   +3 more
europepmc   +1 more source

Regulation of misfolded protein aggregation and degradation by SUMOylation in budding yeast. [PDF]

Mol Biol Cell
Folger A, Gutierrez-Morton E, Kabbaj MH, Campbell MT, Morton G, Megraw TL, Wang Y.   +6 more
europepmc   +1 more source