Results 241 to 250 of about 737,709 (296)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Submolecular Resolution of β‑Sheet Plasticity: Decoding Mutations and PTMs in Protein Aggregation Disorders. [PDF]

ACS Cent Sci
Wang R, Jian Z, Yang Y, Wang C, Yu L, Wang M, Wang C.   +6 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

A Focus on the Link Between Metal Dyshomeostasis, Norepinephrine, and Protein Aggregation. [PDF]

Antioxidants (Basel)
Bacchella C, Capucciati A, Monzani E.
europepmc   +1 more source

UBE2V1 governs aging induced protein aggregation and developmental defects in oocytes and embryos. [PDF]

Commun Biol
Li L, Liu Y, He X, Chen J, Guan X, Han L.   +5 more
europepmc   +1 more source

Comprehensive and Site-Specific Characterization of Protein N-Glycosylation in AD Samples Reveals Its Potential Roles in Protein Aggregation and Synaptic Dysfunction. [PDF]

Anal Chem
Xu X, Tan H, Yin K, Xu S, Wang Z, Serrano GE, Beach TG, Wang X, Peng J, Wu R.   +9 more
europepmc   +1 more source

Amyloid-β disrupts APP-regulated protein aggregation and dissociation from recycling endosomal membranes. [PDF]

EMBO J
Singh PJ, Verma B, Wells A, Mendes CC, Dunn D, Chen YN, Oh J, Blincowe L, Wainwright SM, Fischer R, Fan SJ, Harris AL, Goberdhan DCI, Wilson C.   +13 more
europepmc   +1 more source

Comparing In vitro Protein Aggregation Modelling Using Strategies Relevant to Neuropathologies. [PDF]

Cell Mol Neurobiol
Nadais A, Martins I, Henriques AG, Trigo D, da Cruz E Silva OAB.   +4 more
europepmc   +1 more source

Increased activity of PRMT5-MEP50 complex improves survival of chromosomally unstable cancer cells by increasing tolerance to protein aggregation and proteotoxicity

Suarez Peredo Rodriguez MF, Jilderda LJ, Gaviria Agudelo C, Simon JE, Heberle AM, van Kaam A, Bakker PL, Hong C, Roorda M, Lavoie G, Roux PP, Oeckinghaus A, van Vugt MA, Thedieck K, Foijer F.   +14 more
europepmc   +1 more source