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DNAJ Proteins and Protein Aggregation Diseases

Current Topics in Medicinal Chemistry, 2013
Many neurodegenerative diseases are late onset diseases, associated with aggregation of proteins, implying that aged cells are more susceptible to proteotoxic stress. It is known that with aging, there is a decline in the functionality of chaperone networks and on the other hand, accumulation of damaged proteins occurs.
Vaishali, Kakkar   +2 more
openaire   +2 more sources

Remodeling of Protein Aggregates by Hsp104

Protein & Peptide Letters, 2009
Hsp104 is molecular chaperone in the AAA+ family of ATPases that specializes in the resolubilization and refolding of thermally denatured proteins in yeast. In addition to providing high levels of thermotolerance, Hsp104 plays a pivotal role in the propagation of yeast prions, self-replicating, amyloid-like aggregates that are inherited during mitosis ...
John R, Glover, Ronnie, Lum
openaire   +2 more sources

Protein aggregation

International Journal of Biological Macromolecules, 2017
Ipsita, Roy, Boris I, Kurganov
openaire   +3 more sources

Molecular simulation of protein aggregation

Biotechnology and Bioengineering, 2006
AbstractComputer simulation offers unique possibilities for investigating molecular‐level phenomena difficult to probe experimentally. Drawing from a wealth of studies concerning protein folding, computational studies of protein aggregation are emerging.
Dusan, Bratko   +3 more
openaire   +2 more sources

Aggregated proteins in serum

In Vitro Cellular & Developmental Biology - Animal, 1996
J, Prachar, K, Hlubinova, A, Feldsamova
openaire   +2 more sources

Mechanisms and pathology of protein misfolding and aggregation

Nature Reviews Molecular Cell Biology, 2023
Nikolaos N Louros   +2 more
exaly  

Protein Folding and Aggregation

2005
R. A. Broglia, G. Tiana
openaire   +2 more sources

Protein aggregation and amyloidosis

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2018
openaire   +2 more sources

Cellular strategies for controlling protein aggregation

Nature Reviews Molecular Cell Biology, 2010
Bernd Bukau, Axel Mogk, Jens Tyedmers
exaly  

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